关键词: Aztreonam Carbapenem-resistant Enterobacterales Ceftazidime-avibactam Mediastinitis Paediatric Postsurgical infection

来  源:   DOI:10.1016/j.ijantimicag.2024.107295

Abstract:
Carbapenem-resistant Enterobacterales are being reported increasingly and cause nosocomial infections, which may include postoperative mediastinitis. This paper reports a case of postoperative mediastinitis caused by an Escherichia coli NDM-1 carbapenemase producer in a 13-month-old boy with DiGeorge syndrome. The infection was managed with surgical debridement and antibiotherapy with aztreonam, ceftazidime-avibactam and IV fosfomycin for 6 weeks. The evolution was favourable, without relapse over 10 weeks of follow-up.
摘要:
耐碳青霉烯的肠杆菌越来越多地被报道并引起医院感染,其中可能包括术后纵隔炎。这里,我们报道了一名患有DiGeorge综合征的13个月男童,由大肠杆菌NDM-1碳青霉烯酶生产者引起的术后纵隔炎.感染通过手术清创和氨曲南的抗生素治疗来管理,头孢他啶-阿维巴坦和静脉注射磷霉素6周。随访10周,进展良好,无复发。
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