{Reference Type}: Journal Article
{Title}: Mediastinitis caused by an NDM-1 Escherichia coli in a child with Dacron Sano shunt after pulmonary atresia with ventricular septal defect surgery treated with combination of aztreonam-avibactam.
{Author}: Cousin VL;Miatello J;Sierra R;Sologashvili T;Wacker J;Andrey DO;L'Huillier AG;
{Journal}: Int J Antimicrob Agents
{Volume}: 64
{Issue}: 4
{Year}: 2024 Aug 2
{Factor}: 15.441
{DOI}: 10.1016/j.ijantimicag.2024.107295
{Abstract}: Carbapenem-resistant Enterobacterales are being reported increasingly and cause nosocomial infections, which may include postoperative mediastinitis. This paper reports a case of postoperative mediastinitis caused by an Escherichia coli NDM-1 carbapenemase producer in a 13-month-old boy with DiGeorge syndrome. The infection was managed with surgical debridement and antibiotherapy with aztreonam, ceftazidime-avibactam and IV fosfomycin for 6 weeks. The evolution was favourable, without relapse over 10 weeks of follow-up.