%0 Journal Article
%T Mediastinitis caused by an NDM-1 Escherichia coli in a child with Dacron Sano shunt after pulmonary atresia with ventricular septal defect surgery treated with combination of aztreonam-avibactam.
%A Cousin VL
%A Miatello J
%A Sierra R
%A Sologashvili T
%A Wacker J
%A Andrey DO
%A L'Huillier AG
%J Int J Antimicrob Agents
%V 64
%N 4
%D 2024 Aug 2
%M 39096941
%F 15.441
%R 10.1016/j.ijantimicag.2024.107295
%X Carbapenem-resistant Enterobacterales are being reported increasingly and cause nosocomial infections, which may include postoperative mediastinitis. This paper reports a case of postoperative mediastinitis caused by an Escherichia coli NDM-1 carbapenemase producer in a 13-month-old boy with DiGeorge syndrome. The infection was managed with surgical debridement and antibiotherapy with aztreonam, ceftazidime-avibactam and IV fosfomycin for 6 weeks. The evolution was favourable, without relapse over 10 weeks of follow-up.