Abstract：
Seasonal vaccination remains one of the best interventions to prevent morbidity and mortality from influenza in children. Understanding the characteristics of parents who vaccinate their children can inform communication strategies to encourage immunization. Using a cross-sectional study, we described parental characteristics of people who reported vaccinating their children against influenza during 2018/2019 in a cohort of Canadian digital immunization record users. Data was collected from a free, Pan-Canadian digital vaccination tool, CANImmunize. Eligible accounts contained at least one parental and one \"child/dependent\" record. Each parental characteristic (gender, age, family size, etc) was tested for association with pediatric influenza vaccination, and a multivariate logistic regression model was fit. A total of 6,801 CANImmunize accounts met inclusion criteria. After collapsing the dataset, the final sample contained 11,381 unique dyads. Influenza vaccination was reported for 32.3% of the children and 42.0% of the parents. In the multivariate logistic regression analysis, parents receiving the seasonal influenza vaccine were most strongly associated with reporting pediatric influenza vaccination (OR 17.05, 95% CI 15.08, 19.28). Having a larger family size and fewer transactions during the study period was associated with not reporting pediatric influenza vaccination. While there are several limitations to this large-scale study, these results can help inform future research in the area. Digital technologies may provide a unique and valuable source of vaccine coverage data and to explore associations between individual characteristics and immunization behavior. Policy makers considering digital messaging may want to tailor their efforts based on parental characteristics to further improve pediatric seasonal influenza vaccine uptake.
摘要：
季节性疫苗接种仍然是预防儿童流感发病率和死亡率的最佳干预措施之一。了解为孩子接种疫苗的父母的特征可以为鼓励免疫接种的沟通策略提供信息。使用横断面研究，我们在加拿大数字免疫记录使用者队列中描述了2018/2019年期间报告为其子女接种流感疫苗的人的父母特征.数据是从免费的，泛加拿大数字疫苗接种工具，免疫。符合条件的帐户至少包含一个父母和一个“子女/受抚养人”记录。每个父母特征(性别，年龄,家庭大小,等）进行了与小儿流感疫苗接种的关联测试，拟合多元逻辑回归模型。共有6,801个CANImmunize帐户符合纳入标准。折叠数据集后，最终样本包含11,381个独特的二元组。据报道，32.3%的儿童和42.0%的父母接种了流感疫苗。在多变量逻辑回归分析中，接受季节性流感疫苗的父母与儿童流感疫苗接种报告的相关性最强(OR17.05,95%CI15.08,19.28).在研究期间有更大的家庭规模和更少的交易与未报告儿童流感疫苗接种有关。虽然这项大规模研究有几个局限性，这些结果有助于为该领域未来的研究提供信息。数字技术可以提供疫苗覆盖率数据的独特且有价值的来源，并探索个体特征与免疫行为之间的关联。考虑数字信息的政策制定者可能希望根据父母的特征来调整他们的努力，以进一步提高儿科季节性流感疫苗的摄入量。
