关键词: Brain plasticity Delta band EEG Facial lesions Transplants Wavelet

Mesh : Humans Facial Transplantation Female Male Adult Neuronal Plasticity Electroencephalography / methods Middle Aged Delta Rhythm Cerebral Cortex / physiopathology Young Adult Face

来  源:   DOI:10.1038/s41598-024-67469-w   PDF(Pubmed)

Abstract:
This study focused on detecting the reflections of healing and change in cortex activation in full-face transplantation and lesions patients on EEG activity. Face transplant patients have facial lesions before transplantation and, to identify pre-face transplant patients\' brain activity in the absence of pre-transplant recordings, we used data obtained from pre-transplant facial lesion patients. Ten healthy, four facial lesion and three full-face transplant patients participated in this study. EEG data recorded for four different sensory stimuli (brush from the right face, right hand, left face, and left-hand regions) were analyzed using wavelet packet transform method. EEG waves were analyzed for standard bands. Our findings indicate significant change in the 2-4 Hz frequency range which may be a result of ongoing or previous cortical reorganization for face lesion and transplant patients. Alterations of the delta wave seen in patients with facial lesion and face transplant can also be explained by the intense central plasticity. Our findings show that the delta band differences might be used as a marker in the evaluation of post-transplant cortical plasticity in the future.
摘要:
这项研究的重点是检测全脸移植和病变患者对EEG活动的愈合和皮层激活变化的反映。面部移植患者在移植前有面部病变,为了在没有移植前记录的情况下识别面部移植前患者的大脑活动,我们使用了移植前面部病变患者的数据.十健康,4例面部病变和3例全脸移植患者参与了这项研究.记录四种不同感官刺激的脑电图数据(从右脸上刷,右手,左脸,和左侧区域)使用小波包变换方法进行了分析。分析标准波段的EEG波。我们的发现表明2-4Hz频率范围发生了显着变化,这可能是面部病变和移植患者正在进行或先前进行的皮质重组的结果。面部病变和面部移植患者中出现的δ波变化也可以通过强烈的中枢可塑性来解释。我们的发现表明,δ带差异可能在将来的移植后皮质可塑性评估中用作标记。
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