METHODS: This comparative contralateral study was performed in affected eyes with FUS versus fellow eyes. For each eye parameters such as subfoveal choroidal thickness (SCT), subfoveal choriocapillary thickness (SCCT), central macular thickness (CMT), and central macular volume (CMV) were measured; then the measured values of affected and fellow unaffected eye were compared.
RESULTS: Thirty-seven patients (74 eyes) including 19 females (51.4%) with a mean age of 36.9 ± 7.6 years were enrolled. The mean SCT was lower in the affected eyes (344.51 ± 91.67) than in the fellow (375.59 ± 87.33) with adjusting for duration of disease and axial lengths (P < 0.001). The mean SCCT, CMT, and CMV were higher in eyes with FUS than in fellow eyes (P < 0.05).
CONCLUSIONS: The result of our study demonstrated that affected eyes in patients with FUS tend to have thinner SCT and thicker SCCT and CMT compared to uninvolved fellow eyes.
方法:这项对比研究是在患有FUS的患眼与对侧眼中进行的。对于每个眼睛参数,例如中央凹脉络膜厚度(SCT),中心凹下脉络膜毛细血管厚度(SCCT),黄斑中心厚度(CMT),测量黄斑中心体积(CMV);然后比较受影响和未受影响的眼睛的测量值。
结果:纳入37例患者(74只眼),包括19例女性(51.4%),平均年龄36.9±7.6岁。在调整疾病持续时间和眼轴长度的情况下,受影响的眼睛的平均SCT(344.51±91.67)低于同伴(375.59±87.33)(P<0.001)。平均SCCT,CMT,FUS眼和CMV高于其他眼(P<0.05)。
结论:我们的研究结果表明,与未受累的眼睛相比,FUS患者受累的眼睛倾向于具有更薄的SCT和更厚的SCCT和CMT。