Mesh : Astrocytes / physiology Animals Humans Cognition / physiology Cognitive Dysfunction / physiopathology Neurons / physiology

来  源:   DOI:10.1371/journal.pbio.3002712   PDF(Pubmed)

Abstract:
Glial cells such as astrocytes can modulate neuronal signaling. Astrocytes can also acquire a reactive phenotype that correlates with cognitive impairments in brain diseases. A study in PLOS Biology shows that prolonged activation of astrocytes can trigger both cognitive impairments and a reactive astrocyte phenotype.
摘要:
胶质细胞如星形胶质细胞可以调节神经元信号传导。星形胶质细胞还可以获得与脑疾病中的认知损伤相关的反应性表型。PLOSBiology的一项研究表明,星形胶质细胞的长期激活可以引发认知障碍和反应性星形胶质细胞表型。
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