{Reference Type}: Journal Article {Title}: Activity-induced reactivity of astrocytes impairs cognition. {Author}: Bohmbach K;Henneberger C; {Journal}: PLoS Biol {Volume}: 22 {Issue}: 7 {Year}: 2024 Jul {Factor}: 9.593 {DOI}: 10.1371/journal.pbio.3002712 {Abstract}: Glial cells such as astrocytes can modulate neuronal signaling. Astrocytes can also acquire a reactive phenotype that correlates with cognitive impairments in brain diseases. A study in PLOS Biology shows that prolonged activation of astrocytes can trigger both cognitive impairments and a reactive astrocyte phenotype.