关键词: apoptosis necroptosis necrostatin-1 necrostatins neurological disorders

来  源:   DOI:10.3389/fncel.2024.1408364   PDF(Pubmed)

Abstract:
Necrostatin-1, a small molecular alkaloid, was identified as an inhibitor of necroptosis in 2005. Investigating the fundamental mechanism of Necrostatin-1 and its role in various diseases is of great significance for scientific and clinical research. Accumulating evidence suggests that Necrostatin-1 plays a crucial role in numerous neurological disorders. This review aims to provide a comprehensive overview of the potential functions of Necrostatin-1 in various neurological disorders, offering valuable insights for future research.
摘要:
坏死抑制素-1,一种小分子生物碱,在2005年被确定为坏死的抑制剂。研究Necrostatin-1的作用机制及其在各种疾病中的作用对科学和临床研究具有重要意义。越来越多的证据表明Necrostatin-1在许多神经系统疾病中起着至关重要的作用。这篇综述旨在全面概述Necrostatin-1在各种神经系统疾病中的潜在功能。为未来的研究提供有价值的见解。
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