{Reference Type}: Journal Article {Title}: Necrostatin-1: a promising compound for neurological disorders. {Author}: Chen KQ;Wang SZ;Lei HB;Liu X; {Journal}: Front Cell Neurosci {Volume}: 18 {Issue}: 0 {Year}: 2024 {Factor}: 6.147 {DOI}: 10.3389/fncel.2024.1408364 {Abstract}: Necrostatin-1, a small molecular alkaloid, was identified as an inhibitor of necroptosis in 2005. Investigating the fundamental mechanism of Necrostatin-1 and its role in various diseases is of great significance for scientific and clinical research. Accumulating evidence suggests that Necrostatin-1 plays a crucial role in numerous neurological disorders. This review aims to provide a comprehensive overview of the potential functions of Necrostatin-1 in various neurological disorders, offering valuable insights for future research.