%0 Journal Article %T Necrostatin-1: a promising compound for neurological disorders. %A Chen KQ %A Wang SZ %A Lei HB %A Liu X %J Front Cell Neurosci %V 18 %N 0 %D 2024 %M 38994325 %F 6.147 %R 10.3389/fncel.2024.1408364 %X Necrostatin-1, a small molecular alkaloid, was identified as an inhibitor of necroptosis in 2005. Investigating the fundamental mechanism of Necrostatin-1 and its role in various diseases is of great significance for scientific and clinical research. Accumulating evidence suggests that Necrostatin-1 plays a crucial role in numerous neurological disorders. This review aims to provide a comprehensive overview of the potential functions of Necrostatin-1 in various neurological disorders, offering valuable insights for future research.