PDF(Pubmed)
Abstract：
UNASSIGNED: Clostridioides difficile infections (CDI) continue to pose a challenge for clinicians. Fecal microbiota transplantation (FMT) is an effective treatment option in CDI. Furthermore, recent and ongoing studies suggest potential benefits of FMT in other diseases as well.
UNASSIGNED: We would like to present a novel protocol for encapsulation of lyophilized fecal material. Our method provides with better compliance as well as improved flexibility, storage and safety.
UNASSIGNED: FMT was conducted in 28 patients with an overall success rate of 82,14% using apsules containing lyophilized stool. 16 of patients were given capsules with lessened bacteria counts. The success rate in this group was 93,75%.
UNASSIGNED: The results highlight the still unanswered questions about the mechanism of action and contribute to a wider use of FMT in the clinical praxis and in research.
UNASSIGNED: We would like to present a novel protocol for encapsulation of lyophilized fecal material. Our method provides with better compliance as well as improved flexibility, storage and safety.
UNASSIGNED: FMT was conducted in 28 patients with an overall success rate of 82,14% using apsules containing lyophilized stool. 16 of patients were given capsules with lessened bacteria counts. The success rate in this group was 93,75%.
UNASSIGNED: The results highlight the still unanswered questions about the mechanism of action and contribute to a wider use of FMT in the clinical praxis and in research.
摘要：
■艰难梭菌感染（CDI）继续对临床医生构成挑战。粪便微生物移植（FMT）是CDI的有效治疗选择。此外，最近和正在进行的研究表明，FMT在其他疾病中也有潜在的益处。
我们希望提出一种用于包封冻干粪便材料的新方案。我们的方法提供了更好的合规性以及改进的灵活性，储存和安全。
■使用含有冻干粪便的胶囊对28例患者进行FMT，总成功率为82,14％。16名患者给予细菌计数减少的胶囊。该组的成功率为93,75％。
■结果突出了有关作用机制的仍未解决的问题，并有助于FMT在临床实践和研究中的更广泛使用。
我们希望提出一种用于包封冻干粪便材料的新方案。我们的方法提供了更好的合规性以及改进的灵活性，储存和安全。
■使用含有冻干粪便的胶囊对28例患者进行FMT，总成功率为82,14％。16名患者给予细菌计数减少的胶囊。该组的成功率为93,75％。
■结果突出了有关作用机制的仍未解决的问题，并有助于FMT在临床实践和研究中的更广泛使用。
