%0 Journal Article
%T Encapsulation protocol for fecal microbiota transplantation.
%A Sipos D
%A Varga A
%A Kappéter Á
%A Halda-Kiss B
%A Kása P
%A Pál S
%A Kocsis B
%A Péterfi Z
%J Front Cell Infect Microbiol
%V 14
%N 0
%D 2024
%M 38988813
%F 6.073
%R 10.3389/fcimb.2024.1424376
%X <B>UNASSIGNED: </B>Clostridioides difficile infections (CDI) continue to pose a challenge for clinicians. Fecal microbiota transplantation (FMT) is an effective treatment option in CDI. Furthermore, recent and ongoing studies suggest potential benefits of FMT in other diseases as well.<BR><B>UNASSIGNED: </B>We would like to present a novel protocol for encapsulation of lyophilized fecal material. Our method provides with better compliance as well as improved flexibility, storage and safety.<BR><B>UNASSIGNED: </B>FMT was conducted in 28 patients with an overall success rate of 82,14% using apsules containing lyophilized stool. 16 of patients were given capsules with lessened bacteria counts. The success rate in this group was 93,75%.<BR><B>UNASSIGNED: </B>The results highlight the still unanswered questions about the mechanism of action and contribute to a wider use of FMT in the clinical praxis and in research.