{Reference Type}: Journal Article
{Title}: Encapsulation protocol for fecal microbiota transplantation.
{Author}: Sipos D;Varga A;Kappéter Á;Halda-Kiss B;Kása P;Pál S;Kocsis B;Péterfi Z;
{Journal}: Front Cell Infect Microbiol
{Volume}: 14
{Issue}: 0
{Year}: 2024
{Factor}: 6.073
{DOI}: 10.3389/fcimb.2024.1424376
{Abstract}: <B>UNASSIGNED: </B>Clostridioides difficile infections (CDI) continue to pose a challenge for clinicians. Fecal microbiota transplantation (FMT) is an effective treatment option in CDI. Furthermore, recent and ongoing studies suggest potential benefits of FMT in other diseases as well.<BR><B>UNASSIGNED: </B>We would like to present a novel protocol for encapsulation of lyophilized fecal material. Our method provides with better compliance as well as improved flexibility, storage and safety.<BR><B>UNASSIGNED: </B>FMT was conducted in 28 patients with an overall success rate of 82,14% using apsules containing lyophilized stool. 16 of patients were given capsules with lessened bacteria counts. The success rate in this group was 93,75%.<BR><B>UNASSIGNED: </B>The results highlight the still unanswered questions about the mechanism of action and contribute to a wider use of FMT in the clinical praxis and in research.