关键词: glucose metabolism high-intensity interval exercise lipid metabolism meta-analysis type 2 diabetes mellitus

Mesh : Humans Diabetes Mellitus, Type 2 / metabolism therapy blood High-Intensity Interval Training / methods Lipid Metabolism / physiology Blood Glucose / metabolism Exercise Therapy / methods Exercise / physiology

来  源:   DOI:10.3389/fendo.2024.1360998   PDF(Pubmed)

Abstract:
UNASSIGNED: To evaluate the effects of high-intensity interval training (HIIT) on glycolipid metabolism among type 2 diabetes patients.
UNASSIGNED: HIIT is consistent with an exercise program (65%-90%VO2max or 75%-95% HRmax; exercise cycle≥2 weeks; frequency ≥ 2 times/week). A meta-analysis was conducted utilizing the random effects model to synthesize the data.
UNASSIGNED: A total of 22 RCT studies with 1034 diabetic patients were included. Compared to moderate-intensity aerobic exercise or conventional controls, HIIT yields noteworthy effects on FBG (MD: -0.55; 95% CI: -0.85- -0.25, Hedges\' g =0.98), 2h-PG (MD: -0.36; 95% CI: -0.57- -0.14, Hedges\' g =1.05), FINS (MD: -0.41; 95% CI: -0.79- -0.03, Hedges\' g =1.07), HbA1c (MD: -0.60; 95% CI: -0.84- -0.36, Hedges\' g =2.69), TC (MD: -0.58; 95% CI: -0.80- -0.36, Hedges\' g =2.36), TG (MD: -0.50; 95% CI: -0.86- -0.14, Hedges\' g =1.50), HDL (MD: 0.62; 95% CI: 0.29-0.95, Hedges\' g =1.19) and LDL (MD: -0.31; 95% CI: -0.56- -0.08, Hedges\' g =0.91), all of the above p<0.01.
UNASSIGNED: HIIT has been shown to improve glucose and lipid metabolism in patients with type 2 diabetes, especially in HbA1c, TC, TG, and HDL. For patients between the ages of 40 and 60 with less than 5 years of disease, exercise programs of moderate to longer duration or moderate to high intensity will produce more favorable results.
摘要:
评估高强度间歇训练(HIIT)对2型糖尿病患者糖脂代谢的影响。
HIIT与锻炼计划(65%-90%VO2max或75%-95%HRmax;锻炼周期≥2周;频率≥2次/周)一致。利用随机效应模型进行荟萃分析以综合数据。
共纳入22项针对1034名糖尿病患者的RCT研究。与中等强度有氧运动或常规控制相比,HIIT对FBG产生显著影响(MD:-0.55;95%CI:-0.85--0.25,对冲=0.98),2h-PG(MD:-0.36;95%CI:-0.57--0.14,对冲=1.05),FINS(MD:-0.41;95%CI:-0.79--0.03,对冲=1.07),HbA1c(MD:-0.60;95%CI:-0.84-0.36,对冲=2.69),TC(MD:-0.58;95%CI:-0.80--0.36,对冲=2.36),TG(MD:-0.50;95%CI:-0.86--0.14,对冲=1.50),HDL(MD:0.62;95%CI:0.29-0.95,Hedges\'g=1.19)和LDL(MD:-0.31;95%CI:-0.56-0.08,Hedges\'g=0.91),所有上述p<0.01。
HIIT已被证明可以改善2型糖尿病患者的糖脂代谢,尤其是HbA1c,TC,TG,和HDL。对于年龄在40至60岁之间且患病少于5年的患者,中等至较长持续时间或中等至高强度的锻炼计划将产生更有利的效果。
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