关键词: CD4 count Co-infection Joint model Tuberculosis

Mesh : Humans Ethiopia / epidemiology CD4 Lymphocyte Count Retrospective Studies Male Female Adult HIV Infections / drug therapy epidemiology Hospitals, Teaching Tuberculosis / drug therapy epidemiology Middle Aged Coinfection / epidemiology Young Adult Hemoglobins / analysis

来  源:   DOI:10.4314/ahs.v23i4.2   PDF(Pubmed)

Abstract:
UNASSIGNED: East African regions were highly affected by tuberculosis and the human immunodeficiency virus. The main objective was to identifying the associated factors with tuberculosis and CD4 cell count of patients in Gonder teaching referral hospital, Gonder, Ethiopia.
UNASSIGNED: A retrospective cohort study was conducted on AIDS patients from 1st January 2018 - to 30th January 2020. This study used joint mixed model, and individual profile plot to identify factors and the changeability inside and between patients respectively.
UNASSIGNED: The mean with a standard deviation of weight and a serum hemoglobin concentration of patients were 55.48 (10.21) kilograms and 18.25 (33.028) grams per decilitre respectively.This study shows an opportunistic infection, weight, and serum hemoglobin concentration were significantly associated with the log CD4 cell count and tuberculosis status of patients.
UNASSIGNED: The patient who has other diseases is 5.04 more likely to be co-infected with HIV and TB diseases. And also, the estimated odds of being co-infected in both diseases were increased by 1.14 and 1.05 times when a unit change in weight and hemoglobin respectively. Moreover, the estimated odd of patients who have no other related disease were 51.13% less likely to be co-infected with both diseases.
摘要:
东非地区受结核病和人类免疫缺陷病毒的影响很大。主要目的是确定Gonder教学转诊医院患者的结核病和CD4细胞计数的相关因素,Gonder,埃塞俄比亚。
于2018年1月1日至2020年1月30日对艾滋病患者进行了回顾性队列研究。本研究采用联合混合模型,和个人概况图,分别确定患者内部和患者之间的因素和可变性。
患者体重和血清血红蛋白浓度的标准偏差平均值分别为55.48(10.21)千克和18.25(33.028)克/分升。这项研究显示了机会性感染,体重,和血清血红蛋白浓度与患者的CD4细胞计数和结核状况显著相关。
患有其他疾病的患者更有可能合并感染HIV和TB疾病。而且,当体重和血红蛋白的单位变化时,两种疾病合并感染的估计几率分别增加1.14和1.05倍.此外,在没有其他相关疾病的患者中,两种疾病合并感染的可能性降低了51.13%.
公众号