PDF(Pubmed)
Abstract：
A new polymorph of the diuretic chloro-thia-zide, 6-chloro-1,1-dioxo-2H-1,2,4-benzo-thia-zine-7-sulfonamide, C7H6ClN3O4S2, is described. Crystallized from basic aqueous solution, this monoclinic polymorph is found to be less thermodynamically favoured than the known triclinic polymorph and to feature only N-H⋯O type inter-molecular hydrogen bonds as opposed to the N-H⋯O and N-H⋯N type hydrogen bonds found in the P1 form.
摘要：
利尿剂氯-硫-锌的新多晶型物，6-氯-1,1-二氧代-2H-1,2,4-苯并-thia-zine-7-磺酰胺，描述了C7H6ClN3O4S2。从碱性水溶液中结晶，发现这种单斜多晶型物在热力学上比已知的三斜多晶型物更不受欢迎，并且仅具有N-H_O型分子间氢键，而不是N-H_O和N-H_N型氢键。P1形式。
