{Reference Type}: Journal Article
{Title}: A monoclinic polymorph of chloro-thia-zide.
{Author}: Brydson RKH;Kennedy AR;
{Journal}: Acta Crystallogr E Crystallogr Commun
{Volume}: 80
{Issue}: 0
{Year}: 2024 Jun 1
暂无{DOI}: 10.1107/S2056989024006078
{Abstract}: A new polymorph of the diuretic chloro-thia-zide, 6-chloro-1,1-dioxo-2H-1,2,4-benzo-thia-zine-7-sulfonamide, C7H6ClN3O4S2, is described. Crystallized from basic aqueous solution, this monoclinic polymorph is found to be less thermodynamically favoured than the known triclinic polymorph and to feature only N-H⋯O type inter-molecular hydrogen bonds as opposed to the N-H⋯O and N-H⋯N type hydrogen bonds found in the P1 form.