Abstract：
BACKGROUND: Wounds are a significant source of morbidity among people who use substances (PWUS). This project sought to identify the incidence and severity of wounds among PWUS in the South Bronx, a region of New York City with one of the highest morbidities of substance use disorder.
METHODS: This study recruited PWUS within the past 30 days. Research staff were trained to document the presence and severity of wounds. The primary outcome measure was the incidence of wounds. Acceptability of on-the-street wound care was assessed by the number of participants encountered. The association between participant characteristics and wounds was also evaluated.
RESULTS: In total, 586 PWUS were assessed (19.4 % female: 69 % Hispanic; 23 % Black; 5 % White). Heroin (65.7 %) and psychostimulants (58.3 %) were the most commonly used drugs. Approximately 23 % of outreach recipients disclosed a wound. Among those with a wound, 60.9 % reported one wound, 27.8 % had two wounds, and 11.3 % had three or more wounds. Small wounds (approximately the size of a cherry) were the most common (78.6 %). Recent use of stimulants or heroin, along with intravenous use of any substance were significantly associated with having a wound.
CONCLUSIONS: This study found that drug-related wounds were common among PWUS. Toxicology data from other sources indicate that xylazine was present in the NYC market at the time, though its prevalence among the current sample is difficult to determine. The occurrence and severity of substance-related wounds in NYC should continue to be monitored as a function of changes in the xylazine adulteration.
METHODS: This study recruited PWUS within the past 30 days. Research staff were trained to document the presence and severity of wounds. The primary outcome measure was the incidence of wounds. Acceptability of on-the-street wound care was assessed by the number of participants encountered. The association between participant characteristics and wounds was also evaluated.
RESULTS: In total, 586 PWUS were assessed (19.4 % female: 69 % Hispanic; 23 % Black; 5 % White). Heroin (65.7 %) and psychostimulants (58.3 %) were the most commonly used drugs. Approximately 23 % of outreach recipients disclosed a wound. Among those with a wound, 60.9 % reported one wound, 27.8 % had two wounds, and 11.3 % had three or more wounds. Small wounds (approximately the size of a cherry) were the most common (78.6 %). Recent use of stimulants or heroin, along with intravenous use of any substance were significantly associated with having a wound.
CONCLUSIONS: This study found that drug-related wounds were common among PWUS. Toxicology data from other sources indicate that xylazine was present in the NYC market at the time, though its prevalence among the current sample is difficult to determine. The occurrence and severity of substance-related wounds in NYC should continue to be monitored as a function of changes in the xylazine adulteration.
摘要：
背景：创伤是使用药物（PWUS）的人群中发病率的重要来源。该项目旨在确定南布朗克斯区PWUS伤口的发生率和严重程度，纽约市的一个地区，是物质使用障碍发病率最高的地区之一。
方法：本研究在过去30天内招募了PWUS。对研究人员进行了培训，以记录伤口的存在和严重程度。主要结果指标是伤口的发生率。通过遇到的参与者数量来评估街头伤口护理的可接受性。还评估了参与者特征与伤口之间的关联。
结果：总计，评估了586PWUS（19.4％女性：69％西班牙裔；23％黑人；5％白人）。海洛因(65.7%)和精神兴奋剂(58.3%)是最常用的药物。大约23%的外展接受者披露了伤口。在那些有伤口的人中，60.9%报告有一个伤口，27.8%有两处伤口,11.3%有三处或以上伤口。小伤口（大约樱桃的大小）是最常见的（78.6％）。最近使用兴奋剂或海洛因，静脉内使用任何物质都与伤口明显相关。
结论：这项研究发现，药物相关的创伤在PWUS中很常见。其他来源的毒理学数据表明，赛拉嗪当时存在于纽约市市场，尽管它在当前样本中的患病率很难确定。应继续监测纽约市物质相关伤口的发生和严重程度，作为赛拉嗪掺假变化的函数。
方法：本研究在过去30天内招募了PWUS。对研究人员进行了培训，以记录伤口的存在和严重程度。主要结果指标是伤口的发生率。通过遇到的参与者数量来评估街头伤口护理的可接受性。还评估了参与者特征与伤口之间的关联。
结果：总计，评估了586PWUS（19.4％女性：69％西班牙裔；23％黑人；5％白人）。海洛因(65.7%)和精神兴奋剂(58.3%)是最常用的药物。大约23%的外展接受者披露了伤口。在那些有伤口的人中，60.9%报告有一个伤口，27.8%有两处伤口,11.3%有三处或以上伤口。小伤口（大约樱桃的大小）是最常见的（78.6％）。最近使用兴奋剂或海洛因，静脉内使用任何物质都与伤口明显相关。
结论：这项研究发现，药物相关的创伤在PWUS中很常见。其他来源的毒理学数据表明，赛拉嗪当时存在于纽约市市场，尽管它在当前样本中的患病率很难确定。应继续监测纽约市物质相关伤口的发生和严重程度，作为赛拉嗪掺假变化的函数。
