Substance-Related Disorders

物质相关疾病
  • 文章类型: Journal Article
    健康框架的结构决定因素必须表达反种族主义才能有效,但是种族和族裔不平等被广泛记录,甚至在注重以人为本干预的减少伤害计划中。减少危害战略应表达社会正义和健康公平,抵制污名和歧视,并减轻吸毒人群(PWUD)的边缘化经历。要做到这一点,促进减少伤害的政府和组织政策必须承认种族化毒品使用的历史和持续模式。本文给出了这种种族化的例子,并提供了关于减少伤害规划如何最容易和有效地激励公平、对PWUD的反种族主义护理。
    Structural determinants of health frameworks must express antiracism to be effective, but racial and ethnic inequities are widely documented, even in harm reduction programs that focus on person-centered interventions. Harm reduction strategies should express social justice and health equity, resist stigma and discrimination, and mitigate marginalization experiences among people who use drugs (PWUD). To do so, government and organizational policies that promote harm reduction must acknowledge historical and ongoing patterns of racializing drug use. This article gives examples of such racialization and offers recommendations about how harm reduction programming can most easily and effectively motivate equitable, antiracist care for PWUD.
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  • 文章类型: Journal Article
    迄今为止,还没有一个普遍接受的模型来描述与物质相关的成瘾行为的发展。为了解决这个差距,该研究试图检查主要情绪与成瘾行为倾向之间的关联是否由焦虑依恋风格介导。
    总样本由900名讲德语的非临床成人组成(年龄:M=27;SD=9.60;71.6%为女性)。结构方程模型(SEM)被用来检验主要情绪(悲伤和愤怒)之间的联系,以及潜在变量依恋焦虑和成瘾行为的症状。
    物质使用症状学与更高的依恋焦虑相关(r=0.15),SADNESS(r=0.15),和愤怒(r=0.11)。SADNESS对成瘾行为的影响由依恋焦虑介导(p<0.01),而ANGER对成瘾行为有直接影响(p<0.01)。最终的SEM解释了成瘾行为差异的4%和依恋焦虑的22%。
    我们的研究结果表明,悲伤和愤怒,伴随着依恋焦虑,是导致上瘾行为风险的倾向。然而,虽然愤怒直接影响成瘾行为,悲伤通过其对依恋焦虑的影响起作用。
    UNASSIGNED: To date there is no universally accepted model that describes the development of substance related addictive behavior. In order to address this gap, the study sought to examine whether the association between primary emotions and the inclination toward addictive behavior is mediated by an anxious attachment style.
    UNASSIGNED: The total sample consisted of 900 German speaking non-clinical adults (age: M = 27; SD = 9.60; 71.6% female). Structural Equation Modeling (SEM) was applied to examine the connection between the primary emotions (SADNESS and ANGER), and the latent variables attachment anxiety and symptoms of addictive behavior.
    UNASSIGNED: Substance use symptomatology was correlated with higher attachment anxiety (r = 0.15), SADNESS (r = 0.15), and ANGER (r = 0.11). The effect of SADNESS on addictive behavior is mediated by attachment anxiety (p < 0.01) whereas ANGER had a direct effect on addictive behavior (p < 0.01). The final SEM explains 4% of the variance of addictive behaviors and 22% of attachment anxiety.
    UNASSIGNED: Our findings suggest that both SADNESS and ANGER, along with attachment anxiety, are dispositions that contribute to the risk of engaging in addictive behavior. However, while ANGER directly influences addictive behavior, SADNESS acts through its impact on attachment anxiety.
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  • 文章类型: Journal Article
    背景:药物过量导致的死亡是一个国际问题,2019年全球估计有128,000人死亡。苏格兰是欧洲与毒品有关的死亡率最高的国家,最贫困地区的人比富裕地区的人面临更大的风险。关于数字解决方案的研究很少,特别是从那些使用药物的人的角度来看,他们还获得了减少伤害和无家可归的支持服务。苏格兰数字生命线计划(DLS)为使用/d毒品的弱势群体提供数字设备以与服务连接。
    方法:本文报告了从服务用户的角度对DLS的评估,这些服务用户访问了与药物相关危害风险的服务。使用了混合方法方法,包括在线调查(n=19)和半结构化访谈(n=21)。调查数据采用描述性分析,访谈数据采用归纳编码,由技术通知,人民,组织和宏观环境因素(TPOM)框架,为了调查使用情况,access,和设备的可用性,以及人们对他们的经验和看法。
    结果:大多数参与者居住在社会/理事会住房中(63.2%,n=12),许多人独自生活(68.4%,n=13)。他们主要是40多岁,住在一个城市。参与者描述了对数据隐私的渴望,知识,和教育,并在数字设备上赋予了新生的社会和个人价值。与会者指出,服务提供以人为中心的个性是经常参与服务的原因之一。服务用户的价值感增强,社区感明显,通过该计划开发的联系和归属,包括与服务和设备的交互。
    结论:本文提供了一个独特的视角,记录了服务用户在DLS上的体验。与会者表达了对改善生活的渴望,以及对自己和数字设备的集体和个人责任感。数字包容有可能为服务用户提供安全和建设性地访问服务和社会以改善结果的途径。本文为进一步培养服务用户对这一新兴领域数字解决方案的洞察力奠定了基础。
    BACKGROUND: Deaths due to drug overdose are an international issue, causing an estimated 128,000 global deaths in 2019. Scotland has the highest rate of drug-related deaths in Europe, with those in the most deprived areas at greater risk than those in affluent areas. There is a paucity of research on digital solutions, particularly from the perspective of those who use drugs who additionally access harm reduction and homelessness support services. The Digital Lifelines Scotland programme (DLS) provides vulnerable people who use/d drugs with digital devices to connect with services.
    METHODS: This paper reports on the evaluation of the DLS from the perspective of service users who accessed services for those at risk of drug-related harms. A mixed methods approach was used including an online-survey (n = 19) and semi-structured interviews (n = 21). Survey data were analysed descriptively and interview data through inductive coding, informed by the Technology, People, Organisations and Macroenvironmental factors (TPOM) framework, to investigate the use, access, and availability of devices, and people\'s experiences and perceptions of them.
    RESULTS: Most participants lived in social/council housing (63.2%, n = 12), many lived alone (68.4%, n = 13). They were mainly over 40 years old and lived in a city. Participants described a desire for data privacy, knowledge, and education, and placed a nascent social and personal value on digital devices. Participants pointed to the person-centred individuality of the service provision as one of the reasons to routinely engage with services. Service users experienced an increased sense of value and there was a palpable sense of community, connection and belonging developed through the programme, including interaction with services and devices.
    CONCLUSIONS: This paper presents a unique perspective which documents the experiences of service users on the DLS. Participants illustrated a desire for life improvement and a collective and individual feeling of responsibility towards themselves and digital devices. Digital inclusion has the potential to provide avenues by which service users can safely and constructively access services and society to improve outcomes. This paper provides a foundation to further cultivate the insight of service users on digital solutions in this emerging area.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    托管护理计划,与各州签订合同,覆盖四分之三的医疗补助参保人,在解决美国的毒品流行方面发挥着至关重要的作用。然而,药物使用障碍的福利因医疗补助管理式护理计划而异,目前尚不清楚国家在调节其活动中扮演什么角色。为了解决这个问题,我们调查了33个州和华盛顿州,D.C.,关于2021年医疗补助管理式护理计划的物质使用障碍治疗覆盖率和利用管理要求。大多数州都要求覆盖常见形式的物质使用障碍治疗,并禁止在管理式护理中每年最高限额和注册费用分摊。不到三分之一的州禁止管理式护理计划对每项治疗服务进行事先授权。对于大多数治疗药物,不到三分之二的州禁止事先授权,药物测试,\"首先失败,“或管理式护理中的社会心理治疗要求。我们的研究结果表明,许多州给予管理式护理计划广泛的自由裁量权,对承保的物质使用障碍治疗施加要求,这可能会影响获得救生护理。
    Managed care plans, which contract with states to cover three-quarters of Medicaid enrollees, play a crucial role in addressing the drug epidemic in the United States. However, substance use disorder benefits vary across Medicaid managed care plans, and it is unclear what role states play in regulating their activities. To address this question, we surveyed thirty-three states and Washington, D.C., regarding their substance use disorder treatment coverage and utilization management requirements for Medicaid managed care plans in 2021. Most states mandated coverage of common forms of substance use disorder treatment and prohibited annual maximums and enrollee cost sharing in managed care. Fewer than one-third of states forbade managed care plans from imposing prior authorization for each treatment service. For most treatment medications, fewer than two-thirds of states prohibited prior authorization, drug testing, \"fail first,\" or psychosocial therapy requirements in managed care. Our findings suggest that many states give managed care plans broad discretion to impose requirements on covered substance use disorder treatments, which may affect access to lifesaving care.
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  • 文章类型: Journal Article
    物质使用障碍(SUD)被视为一个连续体,从目标导向和享乐主义的药物使用到对药物摄入失去控制,对身心健康和社会功能产生不利影响。我们的跨学科德国合作研究中心的主要目标是(i)研究触发因素(药物线索,压力源,药物启动)和修饰因素(年龄,性别,身体活动,认知功能,童年的逆境,社会因素,例如孤独和社交接触/互动),纵向调节在现实生活条件下失去和重新控制药物消费的轨迹。(二)研究潜在的行为,疾病轨迹和药物相关行为的认知和神经生物学机制,以及(iii)提供基于非侵入性机制的干预措施。这些目标通过以下方式实现:(A)使用创新的mHealth(移动健康)工具,在900名酒精使用障碍患者的队列中,纵向监测现实生活中触发因素和改变因素对药物消费模式的影响。这种方法将得到成瘾动物模型的补充,在整个疾病轨迹上进行24/7自动化行为监测;即从幼稚状态到吸毒状态再到成瘾或弹性状态。(B)识别和如果适用,关键分子的计算建模,神经生物学和心理机制(例如,认知灵活性降低)调解此类触发因素和改变因素对疾病轨迹的影响。(C)开发和测试非侵入性干预措施(例如,即时自适应干预(JITAI),各种非侵入性脑刺激(NIBS),个性化的身体活动),专门针对重新控制药物摄入的潜在机制。这里,我们将报告第一个资助期最重要的成果,并概述我们未来的研究策略。
    Substance use disorders (SUDs) are seen as a continuum ranging from goal-directed and hedonic drug use to loss of control over drug intake with aversive consequences for mental and physical health and social functioning. The main goals of our interdisciplinary German collaborative research centre on Losing and Regaining Control over Drug Intake (ReCoDe) are (i) to study triggers (drug cues, stressors, drug priming) and modifying factors (age, gender, physical activity, cognitive functions, childhood adversity, social factors, such as loneliness and social contact/interaction) that longitudinally modulate the trajectories of losing and regaining control over drug consumption under real-life conditions. (ii) To study underlying behavioural, cognitive and neurobiological mechanisms of disease trajectories and drug-related behaviours and (iii) to provide non-invasive mechanism-based interventions. These goals are achieved by: (A) using innovative mHealth (mobile health) tools to longitudinally monitor the effects of triggers and modifying factors on drug consumption patterns in real life in a cohort of 900 patients with alcohol use disorder. This approach will be complemented by animal models of addiction with 24/7 automated behavioural monitoring across an entire disease trajectory; i.e. from a naïve state to a drug-taking state to an addiction or resilience-like state. (B) The identification and, if applicable, computational modelling of key molecular, neurobiological and psychological mechanisms (e.g., reduced cognitive flexibility) mediating the effects of such triggers and modifying factors on disease trajectories. (C) Developing and testing non-invasive interventions (e.g., Just-In-Time-Adaptive-Interventions (JITAIs), various non-invasive brain stimulations (NIBS), individualized physical activity) that specifically target the underlying mechanisms for regaining control over drug intake. Here, we will report on the most important results of the first funding period and outline our future research strategy.
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