Abstract：
The dynamics of the composition and antibiotic resistance of the fecal coliform bacteria (FCB) in a typical wastewater treatment plant (WWTP) were investigated concerning the seasonal changes. Results showed that WWTP could remove the FCB concentration by 3∼5 logs within the effluent of 104∼105 CFU/L, but the antibiotic resistant rate of FCB species increased significantly after WWTP. The dominant FCB changed from Escherichia coli in the influent (∼73.0%) to Klebsiella pneumoniae in the effluent (∼53.3%) after WWTP, where the Escherichia coli was removed the most, while Klebsiella pneumoniae was the most persistent. The secondary tank removed the most of FCB (by 3∼4 logs) compared to other processes, but increased all the concerned antibiotic resistant rate. The potential super bugs of FCB community showing resistance to all the target antibiotics were selected in the biological treatment unit of WWTP. The FCB showed the highest multiple antibiotic resistance (92.9%) in total which even increased to 100% in the effluent. Klebsiella has the highest antibiotic resistant rate in FCB, with a multiple antibiotic resistance rate of 98.4%. These indicated that the Klebsiella pneumoniae not just Escherichia coli should be specially emphasized after WWTP concerning the health risk associated with FCB community.
摘要：
研究了典型污水处理厂（WWTP）中粪便大肠杆菌（FCB）的组成和抗生素抗性的动态，并考虑了季节性变化。结果表明，污水处理厂可在104~105CFU/L的出水范围内去除FCB浓度3~5个日志，但WWTP后FCB种的抗生素耐药率显著提高。污水处理厂后，主要的FCB从进水中的大肠杆菌（〜73.0％）转变为出水中的肺炎克雷伯菌（〜53.3％），大肠杆菌被去除最多的地方，而肺炎克雷伯菌是最持久的。与其他工艺相比，二级槽去除了最多的FCB(3~4个日志)，但增加了所有相关的抗生素耐药率。在WWTP的生物处理单元中选择了对所有目标抗生素均具有抗性的FCB群落的潜在超级细菌。FCB显示出最高的多重抗生素抗性（92.9％），在废水中甚至增加到100％。克雷伯菌在FCB中具有最高的抗生素耐药率，多种抗生素耐药率为98.4%。这些表明，关于与FCB社区相关的健康风险，在WWTP之后，应特别强调肺炎克雷伯菌而不仅仅是大肠杆菌。
