Abstract：
Efforts to regulate and monitor emerging contaminants are insufficient because new chemicals are continually brought to market, and many are unregulated and potentially harmful. Domestic wastewater treatment plants are not designed to remove micropollutants and are important sources of emerging contaminants in the aquatic environment. In this study, non-target screening, an unbiased method for analyzing compounds without prior information, was used to identify compounds that may be emitted in wastewater treatment plant effluent and should be monitored. Nine wastewater treatment plants using different treatment methods were studied, and a non-target screening data-processing method was used. The frequencies at which the contaminants were detected and contaminant persistence through the treatment processes were considered, and then the contaminants were prioritized. The predicted no-effect concentration of each prioritized contaminant was used to determine whether further analysis and monitoring of the contaminant was necessary. Quantitative analyses of five compounds (amantadine, atenolol, benzotriazole, diphenhydramine, and sulpiride) were performed using reference standards. Probable molecular formulae and structures were proposed for 17 contaminants, and the risks posed by the contaminants were estimated using predicted no-effect concentrations. The results provide valuable insights into how unregulated micropollutants can be identified and prioritized for monitoring in future studies.
摘要：
监管和监测新出现的污染物的努力是不够的，因为新的化学品不断推向市场，和许多不受管制和潜在的有害。生活污水处理厂的设计目的不是去除微污染物，而是水生环境中新兴污染物的重要来源。在这项研究中,非靶标筛查，在没有先验信息的情况下分析化合物的无偏方法，用于识别可能在废水处理厂废水中排放的化合物，应进行监测。对9个污水处理厂采用不同的处理方法进行了研究,并使用非目标筛查数据处理方法。考虑了污染物被检测到的频率和污染物在处理过程中的持久性，然后优先考虑污染物。每种优先污染物的预测无影响浓度用于确定是否需要进一步分析和监测污染物。五种化合物的定量分析(金刚烷胺，阿替洛尔,苯并三唑,苯海拉明,和舒必利）使用参考标准进行。提出了17种污染物的可能分子式和结构，并使用预测的无效应浓度估算污染物带来的风险。这些结果为如何识别不受管制的微污染物提供了有价值的见解，并在未来的研究中优先进行监测。
