PDF(Pubmed)
Abstract：
Antimicrobial resistance (AMR) is a global public health crisis that impedes the therapeutic effectiveness of available antimicrobial agents. Due to the high burden of infectious diseases and limited resources, especially trained healthcare professionals, low- and middle-income countries (LMICs) are particularly susceptible to the detrimental effects of AMR. Sometimes, as the first and last point of contact for patients seeking treatment for infections, community pharmacists can play a pivotal role in the stewardship required for AMR. This review aims to highlight the contributions made by community pharmacists in LMICs as AMR stewards. The review considers the challenges from the perspectives of limited resources, inadequate training, a lack of policies and regulations, and issues related to patient behavior. Community pharmacists in LMICs could optimize their advocacy contributions by focusing on One Health AMR stewardship. Transformational and actionable patient and population-centric antimicrobial stewardship (AMS) is feasible with the synergy of policymakers and other healthcare providers in the implementation of AMS policies and programs that support community pharmacists in their efforts to promote rational antimicrobial use.
摘要：
抗菌素耐药性（AMR）是一种全球性的公共卫生危机，阻碍了现有抗菌药物的治疗效果。由于传染病负担较高,资源有限,特别是训练有素的医疗保健专业人员，低收入和中等收入国家（LMICs）特别容易受到AMR的不利影响。有时候,作为寻求感染治疗的患者的第一个也是最后一个接触点，社区药剂师可以在AMR所需的管理中发挥关键作用。这篇综述旨在强调社区药剂师作为AMR管理者在LMICs中所做的贡献。审查从资源有限的角度考虑了挑战，训练不足,缺乏政策法规,以及与患者行为有关的问题。低收入国家的社区药剂师可以通过专注于OneHealthAMR管理来优化其宣传贡献。在政策制定者和其他医疗保健提供者的协同作用下，以患者和人群为中心的抗菌素管理（AMS）在实施AMS政策和计划方面是可行的，这些政策和计划支持社区药剂师努力促进合理的抗菌素使用。
