PDF(Pubmed)
Abstract：
This review critically examines the contributions of pupillometry to memory research, primarily focusing on its enhancement of our understanding of memory encoding and retrieval mechanisms mainly investigated with the recognition memory paradigm. The evidence supports a close link between pupil response and memory formation, notably influenced by the type of novelty detected. This proposal reconciles inconsistencies in the literature regarding pupil response patterns that may predict successful memory formation, and highlights important implications for encoding mechanisms. The review also discusses the pupil old/new effect and its significance in the context of recollection and in reflecting brain signals related to familiarity or novelty detection. Additionally, the capacity of pupil response to serve as a true memory signal and to distinguish between true and false memories is evaluated. The evidence provides insights into the nature of false memories and offers a novel understanding of the cognitive mechanisms involved in memory distortions. When integrated with rigorous experimental design, pupillometry can significantly refine theoretical models of memory encoding and retrieval. Furthermore, combining pupillometry with neuroimaging and pharmacological interventions is identified as a promising direction for future research.
摘要：
这篇评论批判性地审查了瞳孔测量对记忆研究的贡献，主要集中在增强我们对记忆编码和检索机制的理解上，主要研究识别记忆范式。证据支持瞳孔反应和记忆形成之间的密切联系，特别受检测到的新奇类型的影响。该建议调和了文献中有关瞳孔反应模式的不一致之处，这些模式可以预测成功的记忆形成。并强调了编码机制的重要意义。该评论还讨论了瞳孔的新旧效应及其在回忆和反映与熟悉或新颖性检测相关的大脑信号中的意义。此外,评估瞳孔反应作为真实记忆信号和区分真实记忆和错误记忆的能力。这些证据提供了对错误记忆性质的见解，并提供了对记忆扭曲所涉及的认知机制的新理解。当与严格的实验设计相结合时，瞳孔测量可以显着完善记忆编码和检索的理论模型。此外，将瞳孔测量与神经影像学和药物干预相结合被认为是未来研究的有希望的方向。
