PDF(Pubmed)
Abstract：
Six new compounds, talamitones A and B (1 and 2), demethyltalamitone B (3), talamiisocoumaringlycosides A and B (4 and 5), and talaminaphtholglycoside (6), together with six known compounds (7-12), were isolated from the marine-derived fungus Talaromyces minnesotensis BTBU20220184. The new structures were characterized by using HRESIMS and NMR. This is the first report of isocoumaringlycoside derivatives from a fungus of the Talaromyces genus. Compounds 5, 6, and 9 showed synergistic antibacterial activity against Staphylococcus aureus.
摘要：
六种新化合物,talamitonesA和B（1和2），去甲基他拉米酮B(3),talamiisocoumaringlycosidesA和B（4和5），和塔拉氨基萘糖苷（6），连同六个已知的化合物（7-12），从海洋真菌TalaromycesminnesotensisBTBU20220184中分离出。新结构通过HRESIMS和NMR表征。这是来自Talaromyces属真菌的异香精糖苷衍生物的首次报道。化合物5、6和9对金黄色葡萄球菌显示出协同抗菌活性。
