%0 Journal Article %T New Secondary Metabolites from Marine-Derived Fungus Talaromyces minnesotensis BTBU20220184. %A Wang W %A Wang J %A Song F %A Jia R %A Wang L %A Xu X %A Yang N %J Mar Drugs %V 22 %N 6 %D 2024 May 23 %M 38921548 %F 6.085 %R 10.3390/md22060237 %X Six new compounds, talamitones A and B (1 and 2), demethyltalamitone B (3), talamiisocoumaringlycosides A and B (4 and 5), and talaminaphtholglycoside (6), together with six known compounds (7-12), were isolated from the marine-derived fungus Talaromyces minnesotensis BTBU20220184. The new structures were characterized by using HRESIMS and NMR. This is the first report of isocoumaringlycoside derivatives from a fungus of the Talaromyces genus. Compounds 5, 6, and 9 showed synergistic antibacterial activity against Staphylococcus aureus.