通过胚胎模型和嵌合体发展人体器官。
关键词: blastocyst complementation extraembryonic endoderm cells hypoblast stem cells interspecies chimeras interspecies organogenesis organ engineering pluripotent stem cells stem cell-based embryo models trophoblast stem cells
Mesh : Animals Humans Chimera / embryology Embryo Implantation Embryo, Mammalian / cytology Embryonic Development Embryonic Stem Cells Models, Biological Organogenesis Organoids Regenerative Medicine Tissue Engineering / methods
来 源:
DOI:10.1016/j.cell.2024.05.027
PDF(Pubmed)