Abstract：
OBJECTIVE: To investigate the impact of mineralized dentin matrix (MDM) on the prognosis on bone regeneration and migration of retained roots after coronectomy.
METHODS: Patients were divided into three groups based on the type of bone graft after coronectomy: Group C (n = 20, collagen), Group T (n = 20, tricalcium phosphate (TCP) + collagen), and Group D (n = 20, MDM + collagen). CBCT scans, conducted immediately and 6 months after surgery, were analyzed using digital software. Primary outcomes, including changes in bone defect depth and retained root migration distance, were evaluated 6 months after surgery.
RESULTS: After 6 months, both Groups D and T exhibited greater reduction of the bone defect and lesser retained root migration than Group C (p < 0.001). Group D had greater regenerated bone volume in the distal 2 mm (73 mm3 vs. 57 mm3, p = 0.011) and lesser root migration (2.18 mm vs. 2.96 mm, p < 0.001) than Group T. The proportion of completely bone embedded retained roots was also greater in Group D than in Group C (70.0% vs. 42.1%, p = 0.003).
CONCLUSIONS: MDM is an appropriate graft material for improving bone defect healing and reducing retained root migration after coronectomy.
CONCLUSIONS: MDM is an autogenous material prepared chairside, which can significantly improve bone healing and reduce the risk of retained root re-eruption. MDM holds promise as a routine bone substitute material after M3M coronectomy.
METHODS: Patients were divided into three groups based on the type of bone graft after coronectomy: Group C (n = 20, collagen), Group T (n = 20, tricalcium phosphate (TCP) + collagen), and Group D (n = 20, MDM + collagen). CBCT scans, conducted immediately and 6 months after surgery, were analyzed using digital software. Primary outcomes, including changes in bone defect depth and retained root migration distance, were evaluated 6 months after surgery.
RESULTS: After 6 months, both Groups D and T exhibited greater reduction of the bone defect and lesser retained root migration than Group C (p < 0.001). Group D had greater regenerated bone volume in the distal 2 mm (73 mm3 vs. 57 mm3, p = 0.011) and lesser root migration (2.18 mm vs. 2.96 mm, p < 0.001) than Group T. The proportion of completely bone embedded retained roots was also greater in Group D than in Group C (70.0% vs. 42.1%, p = 0.003).
CONCLUSIONS: MDM is an appropriate graft material for improving bone defect healing and reducing retained root migration after coronectomy.
CONCLUSIONS: MDM is an autogenous material prepared chairside, which can significantly improve bone healing and reduce the risk of retained root re-eruption. MDM holds promise as a routine bone substitute material after M3M coronectomy.
摘要：
目的：探讨矿化牙本质基质（MDM）对冠状动脉切除术后骨再生和保留根迁移的预后影响。
方法：根据冠状动脉切除术后的植骨类型将患者分为三组：C组（n=20，胶原蛋白），T组（n=20，磷酸三钙（TCP）胶原蛋白），和D组(n=20,MDM+胶原)。CBCT扫描,手术后立即和6个月进行，使用数字软件进行了分析。主要结果,包括骨缺损深度和保留根迁移距离的变化，术后6个月进行评估。
结果：6个月后，与C组相比，D组和T组的骨缺损减少更大，保留的根迁移减少更少（p<0.001）。D组远端2mm的再生骨体积更大（73mm3vs.57mm3，p=0.011）和较小的根部迁移（2.18mmvs.2.96mm,p<0.001)高于T组。D组完全骨包埋保留根的比例也高于C组(70.0%vs.42.1%,p=0.003)。
结论：MDM是改善骨缺损愈合和减少冠状动脉切除术后保留的根部迁移的合适移植材料。
结论：MDM是一种自生材料制备的椅子，这可以显着改善骨愈合，并降低保留根重新萌出的风险。MDM有望成为M3M冠状动脉切除术后的常规骨替代材料。
方法：根据冠状动脉切除术后的植骨类型将患者分为三组：C组（n=20，胶原蛋白），T组（n=20，磷酸三钙（TCP）胶原蛋白），和D组(n=20,MDM+胶原)。CBCT扫描,手术后立即和6个月进行，使用数字软件进行了分析。主要结果,包括骨缺损深度和保留根迁移距离的变化，术后6个月进行评估。
结果：6个月后，与C组相比，D组和T组的骨缺损减少更大，保留的根迁移减少更少（p<0.001）。D组远端2mm的再生骨体积更大（73mm3vs.57mm3，p=0.011）和较小的根部迁移（2.18mmvs.2.96mm,p<0.001)高于T组。D组完全骨包埋保留根的比例也高于C组(70.0%vs.42.1%,p=0.003)。
结论：MDM是改善骨缺损愈合和减少冠状动脉切除术后保留的根部迁移的合适移植材料。
结论：MDM是一种自生材料制备的椅子，这可以显着改善骨愈合，并降低保留根重新萌出的风险。MDM有望成为M3M冠状动脉切除术后的常规骨替代材料。
