PDF(Pubmed)
Abstract：
BACKGROUND: This case describes the youngest patient documented in the literature who presented with a giant hydatidiform mole, effectively addressed through conservative treatment.
METHODS: Our department received a 20-year-old Caucasian patient who was admitted due to significant metrorrhagia in an undisclosed pregnancy. During examination, we identified a massive, highly vascularized hydatidiform mole measuring 22 cm (cm). We performed a surgical dilatation and curettage. The anatomopathological findings confirmed the presence of a complete hydatidiform mole (CHM). Following the established guidelines, we conducted weekly monitoring of human chorionic gonadotropin (hCG). Unfortunately, the patient discontinued the follow-up and became pregnant again before achieving hCG negativation.
CONCLUSIONS: This case suggests that conservative treatment is a viable option regardless of the size of gestational trophoblastic disease (GTD), especially when the preservation of fertility is a crucial consideration, as effectively demonstrated in our case.
METHODS: Our department received a 20-year-old Caucasian patient who was admitted due to significant metrorrhagia in an undisclosed pregnancy. During examination, we identified a massive, highly vascularized hydatidiform mole measuring 22 cm (cm). We performed a surgical dilatation and curettage. The anatomopathological findings confirmed the presence of a complete hydatidiform mole (CHM). Following the established guidelines, we conducted weekly monitoring of human chorionic gonadotropin (hCG). Unfortunately, the patient discontinued the follow-up and became pregnant again before achieving hCG negativation.
CONCLUSIONS: This case suggests that conservative treatment is a viable option regardless of the size of gestational trophoblastic disease (GTD), especially when the preservation of fertility is a crucial consideration, as effectively demonstrated in our case.
摘要：
背景：该病例描述了文献中记录的最年轻的患者，患有巨大的葡萄胎，通过保守治疗有效解决。
方法：我们部门接收了一名20岁的白种人患者，该患者因严重的子宫出血而入院。考试期间,我们发现了一个巨大的，高度血管化的葡萄胎，尺寸为22厘米（厘米）。我们进行了手术扩张和刮宫。解剖病理学发现证实了完全葡萄胎（CHM）的存在。遵循既定准则，我们每周进行人绒毛膜促性腺激素(hCG)的监测.不幸的是,患者停止随访,在取得hCG阴性之前再次怀孕.
结论：该病例表明，无论妊娠滋养细胞疾病（GTD）的大小如何，保守治疗都是可行的选择。尤其是当保护生育能力是一个至关重要的考虑因素时，正如我们的案例所证明的那样。
方法：我们部门接收了一名20岁的白种人患者，该患者因严重的子宫出血而入院。考试期间,我们发现了一个巨大的，高度血管化的葡萄胎，尺寸为22厘米（厘米）。我们进行了手术扩张和刮宫。解剖病理学发现证实了完全葡萄胎（CHM）的存在。遵循既定准则，我们每周进行人绒毛膜促性腺激素(hCG)的监测.不幸的是,患者停止随访,在取得hCG阴性之前再次怀孕.
结论：该病例表明，无论妊娠滋养细胞疾病（GTD）的大小如何，保守治疗都是可行的选择。尤其是当保护生育能力是一个至关重要的考虑因素时，正如我们的案例所证明的那样。
