Abstract：
Mendez-Gomez et al. recently demonstrated the transformative potential of RNA-lipid particle aggregates (RNA-LPAs) in immunotherapy. By reprogramming the tumor microenvironment (TME) and potentiating antitumor immunity, RNA-LPAs target primary tumors and elicit robust systemic immunity. This innovative platform holds promise for translating preclinical success into tangible clinical benefits.
摘要：
Mendez-Gomez等人.最近证明了RNA-脂质颗粒聚集体（RNA-LPAs）在免疫治疗中的转化潜力。通过重新编程肿瘤微环境（TME）和增强抗肿瘤免疫力，RNA-LPAs靶向原发性肿瘤并引发强大的全身免疫。这一创新平台有望将临床前成功转化为切实的临床益处。
