PDF(Pubmed)
Abstract：
The Department of Defense Global Respiratory Pathogen Surveillance Program conducts continuous surveillance for influenza, severe acute respiratory syndrome 2 (SARS-CoV-2), and other respiratory pathogens at 104 sentinel sites across the globe. These sites submitted 65,475 respiratory specimens for clinical diagnostic testing during the 2021-2022 surveillance season. The predominant influenza strain was influenza A(H3N2) (n=777), of which 99.9% of strains were in clade 3C.2a1b.2a2. A total of 21,466 SARSCoV-2-positive specimens were identified, and 12,225 of the associated viruses were successfully sequenced. The Delta variant predominated at the start of the season, until December 2021, when Omicron became dominant. Most circulating SARS-CoV-2 viruses were subsequently held by Omicron sublineages BA.1, BA.2, and BA.5 during the season. Clinical manifestation, obtained through a self-reported questionnaire, found that cough, sinus congestion, and runny nose complaints were the most common symptoms presenting among all pathogens. Sentinel surveillance can provide useful epidemiological data to supplement other disease monitoring activities, and has become increasingly useful with increasing numbers of individuals utilizing COVID-19 rapid self-test kits and reductions in outpatient visits for routine respiratory testing.
摘要：
国防部全球呼吸道病原体监测计划对流感进行持续监测,严重急性呼吸系统综合症2（SARS-CoV-2），以及全球104个哨点的其他呼吸道病原体。在2021-2022年监测季节期间，这些网站提交了65,475份呼吸道标本进行临床诊断测试。主要的流感毒株是甲型流感（H3N2）（n=777），其中99.9％的菌株位于进化枝3C.2a1b.2。共鉴定出21,466份SARSCoV-2阳性标本,并成功测序了12,225种相关病毒。三角洲变种在本赛季开始时占主导地位，直到2021年12月，Omicron成为主导。在该季节中，大多数流行的SARS-CoV-2病毒随后由Omicron亚谱系BA.1，BA.2和BA.5持有。临床表现,通过自我报告的问卷获得，发现咳嗽,鼻窦充血,流鼻涕是所有病原体中最常见的症状。哨点监测可以提供有用的流行病学数据，以补充其他疾病监测活动，随着越来越多的人使用COVID-19快速自检试剂盒，以及常规呼吸检测的门诊量减少，它变得越来越有用。
