Abstract：
A magnetic MXene aerogel (Fe3O4@MXene@PEI) was prepared by crosslinking amino modified MXene with polyethyleneimine using epichlorohydrin as a cross-linker. Adsorption properties of Fe3O4@MXene@PEI aerogel for phenolic acids were evaluated by adsorption kinetics and isotherms experiments, showing that the high adsorption affinity was governed by multilayer chemisorption process. An efficient MSPE/HPLC method was developed for the determination of phenolic acids with excellent selectivity, good linearity (0.025-5.0 μg mL-1), low LODs (0.007-0.017 μg mL-1), and satisfactory recoveries (80.0-120.0 %). Moreover, the antioxidant activity of the Fe3O4@MXene@PEI purified compounds was superior to that of the conventional method as demonstrated by the results of scavenging experiments on 2,2 -diphenyl-1-picrylhydrazyl radical scavenging assay. Finally, 65 organic acids were identified in the Fe3O4@MXene@PEI treated honeysuckle extracts by UHPLC-Q-Exactive Orbitrap MS/MS analysis. The proposed sorbent exhibits remarkable promise for the selective separation and purification of organic acids from herbal products.
摘要：
通过使用表氯醇作为交联剂将氨基改性的MXene与聚乙烯亚胺交联，制备了磁性MXene气凝胶（Fe3O4@MXene@PEI）。通过吸附动力学和等温线实验评价了Fe3O4@MXene@PEI气凝胶对酚酸的吸附性能,表明高吸附亲和力受多层化学吸附过程控制。建立了一种高效的MSPE/HPLC法测定酚酸，具有良好的选择性，线性良好（0.025-5.0μgmL-1），低LOD（0.007-0.017μgmL-1），和令人满意的回收率（80.0-120.0%）。此外，Fe3O4@MXene@PEI纯化化合物的抗氧化活性优于常规方法，如2,2-二苯基-1-吡啶酰肼自由基清除试验的清除实验结果表明。最后,通过UHPLC-Q-ExactiveOrbitrapMS/MS分析，在Fe3O4@MXene@PEI处理的金银花提取物中鉴定出65种有机酸。所提出的吸附剂对于从草药产品中选择性分离和纯化有机酸具有显着的前景。
