{Reference Type}: Journal Article
{Title}: Selective extraction and analysis of phenolic acids in herbal plants using Fe3O4@MXene@PEI aerogel.
{Author}: Hu K;Liu X;Ma H;Zhao D;Song J;Zeng H;Zhang Z;
{Journal}: Talanta
{Volume}: 277
{Issue}: 0
{Year}: 2024 Sep 1
{Factor}: 6.556
{DOI}: 10.1016/j.talanta.2024.126344
{Abstract}: A magnetic MXene aerogel (Fe3O4@MXene@PEI) was prepared by crosslinking amino modified MXene with polyethyleneimine using epichlorohydrin as a cross-linker. Adsorption properties of Fe3O4@MXene@PEI aerogel for phenolic acids were evaluated by adsorption kinetics and isotherms experiments, showing that the high adsorption affinity was governed by multilayer chemisorption process. An efficient MSPE/HPLC method was developed for the determination of phenolic acids with excellent selectivity, good linearity (0.025-5.0 μg mL-1), low LODs (0.007-0.017 μg mL-1), and satisfactory recoveries (80.0-120.0 %). Moreover, the antioxidant activity of the Fe3O4@MXene@PEI purified compounds was superior to that of the conventional method as demonstrated by the results of scavenging experiments on 2,2 -diphenyl-1-picrylhydrazyl radical scavenging assay. Finally, 65 organic acids were identified in the Fe3O4@MXene@PEI treated honeysuckle extracts by UHPLC-Q-Exactive Orbitrap MS/MS analysis. The proposed sorbent exhibits remarkable promise for the selective separation and purification of organic acids from herbal products.