PDF(Pubmed)
Abstract：
Akabane disease is an arthropod-borne viral disease that affects ruminants. This teratogenic pathogen causes severe economic losses in ruminants worldwide and in Iran; however, it has not received enough attention in Fars province, Iran. Therefore, this study aimed to determine the influence of age, gender, climate, farming system, and history of abortions on the seroprevalence of the Akabane disease in sheep and goats in Fars province. In the present study, Fars province was divided into three climates, and three cities were randomly selected from each climatic region. In each city, two epidemiologic units were selected, and all sheep and goats in each unit were sampled. Overall, 540 serum samples (391 sheep and 149 goats) were collected and examined with the commercial ELISA kit. The results showed that 83 out of 540 (15.4%) samples were seropositive and had antibodies against the Akabane virus (AKAV). The effect of gender and age on the rate of the AKAV was not significant. Animals in warm climates were 4.218 times more likely to have antibodies against the AKAV than animals in cold climates. Females were 1.32 times more likely to exhibit seropositivity. The odds of AKAV infection were higher in animals with an abortion history than in healthy animals. The findings of the present study indicated that the prevalence of the AKAV was high in small ruminants in Fars province. Therefore, it is necessary to conduct more studies to control the risk factors involved in the spread of this virus.
摘要：
Akabane病是一种节肢动物传播的病毒性疾病，会影响反刍动物。这种致畸病原体在全世界和伊朗的反刍动物中造成严重的经济损失；然而，它在法尔斯省没有得到足够的重视，伊朗。因此,这项研究旨在确定年龄的影响，性别,气候,耕作制度,以及Fars省绵羊和山羊的Akabane病血清流行率的流产史。在本研究中,法尔斯省分为三种气候，从每个气候区域随机选择三个城市。在每个城市，选择了两个流行病学单位，每个单位的所有绵羊和山羊都被取样。总的来说,收集540份血清样品(391只绵羊和149只山羊)并用商业ELISA试剂盒检测。结果显示,540个样品中的83个(15.4%)是血清阳性的,并且具有针对Akabane病毒(AKAV)的抗体。性别、年纪对AKAV产生率的影响不显著。温暖气候下的动物比寒冷气候下的动物更可能具有针对AKAV的抗体的4.218倍。女性表现出血清阳性的可能性是1.32倍。有流产史的动物的AKAV感染几率高于健康动物。本研究的结果表明，在法尔斯省的小反刍动物中，AKAV的患病率很高。因此,有必要进行更多的研究来控制这种病毒传播的危险因素。
