PDF(Pubmed)
Abstract：
This preregistered ex vivo investigation examined the dentinal hybrid layer formation of a resinous infiltrant (Icon), with reference to both thickness (HLT) and homogeneity when combined with modified tunnel preparation (occlusal cavity only) and internal/external caries infiltration. The adhesives Syntac and Scotchbond MP were used as controls (Groups 1 and 3) or in combination with Icon (Groups 2 and 4). A split-tooth design using healthy third molars from 20 donors resulted in 20 prepared dentine cavities per experimental group. The cavity surfaces (n = 80) were etched (37% H3PO4), rinsed, and air-dried. Rewetting with ethanol was followed by application of the respective primers. After labeling with fluorescent dyes, either Syntac Adhesive/Heliobond or Scotchbond MP Adhesive was used alone or supplemented with Icon. HLT, as evaluated by scanning electron microscopy, did not significantly differ (P > 0.05), and confocal laser scanning microscopy revealed homogeneously mixed/polymerized resin-dentine interdiffusion zones in all groups. Icon can be successfully integrated into an ethanol-wet dentine bonding strategy, and will result in compact and homogeneous hybrid layers of comparable thickness considered equivalent to the non-Icon controls, thus allowing for preservation of the tooth\'s marginal ridge and interdental space in the case of internal/external infiltration of proximal caries.
摘要：
这项预先注册的离体研究检查了树脂渗透剂（图标）的牙本质杂化层形成，当与改良的隧道准备（仅咬合腔）和内部/外部龋齿浸润相结合时，参考厚度（HLT）和均匀性。粘合剂Syntac和ScotchbondMP用作对照(组1和3)或与图标组合(组2和4)。使用来自20个供体的健康第三磨牙进行分裂牙设计，每个实验组产生20个制备的牙本质腔。腔表面（n=80）被蚀刻（37%H3PO4），冲洗,空气干燥。在用乙醇再润湿之后施加相应的引物。用荧光染料标记后，Syntac粘合剂/Heliobond或ScotchbondMP粘合剂单独使用或补充Icon。HLT,通过扫描电子显微镜评估，差异不显著(P>0.05)，和共聚焦激光扫描显微镜显示所有组中均匀混合/聚合的树脂-牙本质相互扩散区。图标可以成功地整合到乙醇-湿牙本质结合策略中，并将导致紧凑和均匀的混合层的可比厚度被认为相当于非图标控制，因此，在近端龋齿的内部/外部浸润的情况下，可以保留牙齿的边缘脊和齿间间隙。
