慢性纺锤体组装检查点激活导致骨髓抑制和胃肠道萎缩。
关键词: Apoptosis BH3-only Proteins MAD2 Mitosis Spindle Assembly Checkpoint
Mesh : Animals Bcl-2-Like Protein 11 / metabolism genetics Mice Mad2 Proteins / metabolism genetics Apoptosis Regulatory Proteins / metabolism genetics M Phase Cell Cycle Checkpoints Proto-Oncogene Proteins c-bcl-2 / metabolism genetics Apoptosis Atrophy Proto-Oncogene Proteins / metabolism genetics Mitosis BH3 Interacting Domain Death Agonist Protein / metabolism genetics Cdc20 Proteins / metabolism genetics Bone Marrow / pathology metabolism Membrane Proteins / metabolism genetics Tumor Suppressor Proteins
来 源:
DOI:10.1038/s44319-024-00160-3
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