关键词: Antivenom compartment syndrome copperhead envenomation fasciotomy pit viper rattlesnake snakebite surgery

Mesh : Snake Bites / epidemiology Texas / epidemiology Fasciotomy Humans Antivenins / therapeutic use Male Adult Animals Female Middle Aged Compartment Syndromes / etiology epidemiology surgery Young Adult Child Adolescent Crotalinae Child, Preschool Aged Poison Control Centers / statistics & numerical data Crotalid Venoms / antagonists & inhibitors Databases, Factual

来  源:   DOI:10.1080/15563650.2024.2338559

Abstract:
UNASSIGNED: North American pit viper envenomation occurs over 4,000 times annually in the United States, with polyvalent Fab antivenom being the primary treatment. Fasciotomy is occasionally performed due to concerns about compartment syndrome. We utilized our direct access to Texas Poison Center Network data to create a new snakebite abstraction form and database on relevant available information between 2004 and 2021 and to identify, describe, and estimate the incidence of fasciotomy following pit viper envenomation in Texas.
UNASSIGNED: We searched the Texas Poison Center Network database for cases during 2004-2021 using keywords such as fasciotomy, surgery, compartment pressure, and compartment syndrome. Descriptive statistics summarized the data.
UNASSIGNED: Of 16,911 reported envenomations, 0.69 percent involved fasciotomies (n = 117). Most common bite sites were digits/hands and lower extremities. Patients who underwent fasciotomy were typically male, aged 20-59, and 10 years younger than the total snakebite population. Only 6 percent of reported compartment syndrome cases had a compartment pressure measurement. Antivenom was administered in 101 (86.3 percent) cases, 92 (91.1 percent) of which received only Fab antivenom product. Patients with bites from rattlesnakes (47.9 percent) were associated with most fasciotomies.
UNASSIGNED: Our findings suggest a potential increase in snakebite exposures, accompanied by a decrease in fasciotomies. Overall, copperheads constituted the majority of snakebites, but most fasciotomies were from rattlesnake envenomations (47.9 percent). In this cohort, compartment syndrome diagnosis and decisions regarding fasciotomy were primarily based on clinical evaluation/surgeon expertise without compartment pressure measurements. Despite the efficacy of antivenom, only 86.3 percent of patients in our study received antivenom.
UNASSIGNED: Fasciotomy after North American pit viper envenomation in Texas is uncommon (0.69 percent) and has decreased over time, possibly due to increased antivenom use or surgeon comfort with nonsurgical management.
摘要:
在美国,每年发生4,000次以上的北美毒蛇事件,多价Fab抗蛇毒血清是主要治疗方法。由于担心筋膜室综合征,偶尔进行筋膜切开术。我们利用对得克萨斯毒物中心网络数据的直接访问,在2004年至2021年之间创建了一个新的蛇咬伤抽象表格和数据库,描述,并估计在得克萨斯州,pit蛇毒后筋膜切开术的发生率。
我们在2004-2021年期间使用诸如筋膜切开术之类的关键字搜索了德克萨斯州毒物中心网络数据库中的病例,手术,舱室压力,和室综合征。描述性统计数据总结了数据。
报告的16,911个毒物,0.69%涉及筋膜切开术(n=117)。最常见的咬伤部位是手指/手和下肢。接受筋膜切开术的患者通常是男性,年龄在20-59岁之间,比蛇咬伤总数小10岁。报告的室综合征病例中只有6%进行了室压测量。101例(86.3%)服用抗蛇毒血清,92(91.1%)只收到Fab抗蛇毒血清产品。响尾蛇咬伤的患者(47.9%)与大多数筋膜切开术有关。
我们的研究结果表明,蛇咬伤的暴露量可能会增加,伴随着筋膜切除术的减少。总的来说,铜头构成了大多数蛇咬伤,但是大多数筋膜切开术来自响尾蛇毒素(47.9%)。在这个队列中,筋膜室综合征的诊断和有关筋膜切开术的决定主要基于临床评估/外科医生的专业知识,而无需测量筋膜室压力。尽管抗蛇毒血清有功效,在我们的研究中,只有86.3%的患者接受了抗蛇毒血清.
德克萨斯州的北美毒蛇毒液后的筋膜切开术并不常见(0.69%),并且随着时间的流逝而减少,可能是由于抗蛇毒血清使用增加或外科医生对非手术治疗的舒适度。
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