Abstract：
This study investigated the effects of octenyl succinic anhydride (OSA)-starch-fatty acid (FA) interactions on the structural, digestibility and release characteristics of high amylose corn starch (HAS). FTIR and XRD analysis showed that the hydrophobic interaction between HAS and FA promoted the covalent binding between OSA and HAS. With the increasing of the FA chain length, the complex index, degree of substitution, R1047/1022 and relative crystallinity of OSA-HAS-FA increased first and then decreased, whereas the first-order rate coefficient and percentage of digested in infinite time showed an opposite trend. Structural changes and the molecular interactions of OSA-HAS-FA with 12‑carbon FA resulted in highest resistant starch content (45.43%) and encapsulation efficiency of curcumin (Cur) (47.98%). In vitro release test revealed that Cur could be gradually released from OSA-HAS-FA in simulated gastric, intestinal and colonic fluids. Results provided novel insights into HAS-FA complex grafted with OSA as carrier for colon-specific of functional materials.
摘要：
这项研究调查了辛烯基琥珀酸酐（OSA）-淀粉-脂肪酸（FA）相互作用对结构的影响，高直链淀粉玉米淀粉(HAS)的消化率和释放特性。FTIR和XRD分析表明，HAS和FA之间的疏水相互作用促进了OSA和HAS之间的共价结合。随着FA链长度的增加,复杂指数，替代程度,R1047/1022和OSA-HAS-FA的相对结晶度先升高后降低,而在无限时间内，一阶速率系数和消化百分比表现出相反的趋势。OSA-HAS-FA与12碳FA的结构变化和分子相互作用导致最高的抗性淀粉含量（45.43％）和姜黄素（Cur）的包封率（47.98％）。体外释放试验表明，Cur可以在模拟胃中从OSA-HAS-FA中逐渐释放，肠液和结肠液。结果为OSA接枝的HAS-FA复合物作为结肠特异性功能材料的载体提供了新的见解。
