PDF(Pubmed)
Abstract：
Background and objectives: while acute ischemic stroke is the leading cause of epilepsy in the elderly population, data about its risk factors have been conflicting. Therefore, the aim of our study is to determine the association of early and late epileptic seizures after acute ischemic stroke with cerebral cortical involvement and electroencephalographic changes. Materials and methods: a prospective cohort study in the Hospital of the Lithuanian University of Health Sciences Kaunas Clinics Department of Neurology was conducted and enrolled 376 acute ischemic stroke patients. Data about the demographical, clinical, radiological, and encephalographic changes was gathered. Patients were followed for 1 year after stroke and assessed for late ES. Results: the incidence of ES was 4.5%, the incidence of early ES was 2.7% and the incidence of late ES was 2.4%. The occurrence of early ES increased the probability of developing late ES. There was no association between acute cerebral cortical damage and the occurrence of ES, including both early and late ES. However, interictal epileptiform discharges were associated with the occurrence of ES, including both early and late ES.
摘要：
配景与目标：而急性缺血性脑卒中是老年人群癫痫的主要病因，有关其风险因素的数据一直相互矛盾。因此,本研究的目的是确定急性缺血性卒中后早期和晚期癫痫发作与大脑皮层受累和脑电图改变的关系.材料和方法：在立陶宛健康科学大学医院Kaunas神经内科诊所进行了一项前瞻性队列研究，纳入了376例急性缺血性卒中患者。有关人口统计的数据，临床,放射学,收集了脑电图变化。患者在卒中后随访1年，并评估晚期ES。结果:ES发生率为4.5%,早期ES的发生率为2.7%,晚期ES的发生率为2.4%.早期ES的发生增加了发展晚期ES的可能性。急性大脑皮质损害与ES的发生无相关性,包括早期和晚期ES。然而,发作间癫痫样放电与ES的发生有关，包括早期和晚期ES。
