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Abstract：
BACKGROUND: Knowledge of pharmacovigilance (PV) and adverse drug reactions (ADRs) are the core competencies that healthcare students should acquire during their studies. The objective of this study was to assess attitudes towards and knowledge of PV and ADRs among healthcare students in China.
METHODS: An online, cross-sectional survey was conducted nationally among healthcare students in China from April through October 2023. Knowledge of PV and ADRs was assessed using a questionnaire based on current PV guidelines. We performed logistic regression analysis to determine the potential factors related to knowledge of and attitudes towards PV and ADRs.
RESULTS: A total of 345 students were included in the analysis. Among the healthcare students who participated in the survey, 225 (65.22%) students correctly defined PV, while only 68 (19.71%) had a correct understanding of ADRs. Among all respondents included in the analysis, only 71 (20.58%) reported having taken a PV course. Pharmacy students were more likely to have taken PV courses at a university and to demonstrate superior knowledge compared to other healthcare students. The logistic regression model revealed that the significant predictors of a higher level of PV knowledge were being female (odds ratio [OR]: 1.76; 95% confidence interval (CI): 1.06-2.92; P value: 0.028) and having previously taken PV-related courses (OR: 2.00; 95% CI: 1.06-3.80; P value: 0.034).
CONCLUSIONS: This study revealed that healthcare students\' knowledge of PV and ADRs is unsatisfactory. However, there were a limited number of universities providing PV education. Given the vital role of healthcare professionals in identifying and reporting ADRs, our findings raise significant concerns. Hence, more efforts should be made to enhance PV education for future healthcare professionals.
METHODS: An online, cross-sectional survey was conducted nationally among healthcare students in China from April through October 2023. Knowledge of PV and ADRs was assessed using a questionnaire based on current PV guidelines. We performed logistic regression analysis to determine the potential factors related to knowledge of and attitudes towards PV and ADRs.
RESULTS: A total of 345 students were included in the analysis. Among the healthcare students who participated in the survey, 225 (65.22%) students correctly defined PV, while only 68 (19.71%) had a correct understanding of ADRs. Among all respondents included in the analysis, only 71 (20.58%) reported having taken a PV course. Pharmacy students were more likely to have taken PV courses at a university and to demonstrate superior knowledge compared to other healthcare students. The logistic regression model revealed that the significant predictors of a higher level of PV knowledge were being female (odds ratio [OR]: 1.76; 95% confidence interval (CI): 1.06-2.92; P value: 0.028) and having previously taken PV-related courses (OR: 2.00; 95% CI: 1.06-3.80; P value: 0.034).
CONCLUSIONS: This study revealed that healthcare students\' knowledge of PV and ADRs is unsatisfactory. However, there were a limited number of universities providing PV education. Given the vital role of healthcare professionals in identifying and reporting ADRs, our findings raise significant concerns. Hence, more efforts should be made to enhance PV education for future healthcare professionals.
摘要：
背景：药物警戒（PV）和药物不良反应（ADR）知识是医疗保健专业学生在学习期间应获得的核心能力。这项研究的目的是评估中国医疗保健学生对PV和ADR的态度和知识。
方法：在线，从2023年4月到10月，在中国的医疗保健学生中进行了全国横断面调查。使用基于当前PV指南的问卷评估PV和ADR的知识。我们进行了logistic回归分析，以确定与PV和ADR的知识和态度相关的潜在因素。
结果：共有345名学生被纳入分析。在参与调查的医护学生中，225名(65.22%)学生正确定义PV，只有68人(19.71%)对ADR有正确认识。在分析中包括的所有受访者中，只有71人（20.58%）报告参加了PV课程。与其他医疗保健专业的学生相比，药学专业的学生更有可能在大学学习PV课程，并表现出卓越的知识。逻辑回归模型显示，PV知识水平较高的重要预测因素是女性（比值比[OR]：1.76；95％置信区间（CI）：1.06-2.92；P值：0.028）和以前参加过PV相关课程（OR：2.00；95％CI：1.06-3.80；P值：0.034）。
结论：这项研究表明，医疗保健专业学生对PV和ADR的了解并不令人满意。然而,提供光伏教育的大学数量有限。鉴于医疗保健专业人员在识别和报告ADR方面的重要作用，我们的发现引起了人们的极大关注.因此，应加大力度加强未来医疗保健专业人员的光伏教育。
方法：在线，从2023年4月到10月，在中国的医疗保健学生中进行了全国横断面调查。使用基于当前PV指南的问卷评估PV和ADR的知识。我们进行了logistic回归分析，以确定与PV和ADR的知识和态度相关的潜在因素。
结果：共有345名学生被纳入分析。在参与调查的医护学生中，225名(65.22%)学生正确定义PV，只有68人(19.71%)对ADR有正确认识。在分析中包括的所有受访者中，只有71人（20.58%）报告参加了PV课程。与其他医疗保健专业的学生相比，药学专业的学生更有可能在大学学习PV课程，并表现出卓越的知识。逻辑回归模型显示，PV知识水平较高的重要预测因素是女性（比值比[OR]：1.76；95％置信区间（CI）：1.06-2.92；P值：0.028）和以前参加过PV相关课程（OR：2.00；95％CI：1.06-3.80；P值：0.034）。
结论：这项研究表明，医疗保健专业学生对PV和ADR的了解并不令人满意。然而,提供光伏教育的大学数量有限。鉴于医疗保健专业人员在识别和报告ADR方面的重要作用，我们的发现引起了人们的极大关注.因此，应加大力度加强未来医疗保健专业人员的光伏教育。
