目的:高血压非常普遍,是心血管疾病的主要危险因素。在社会经济地位较低(SES)的个体中,高血压的负担较高,然而,睡眠在了解高血压的社会经济差异中的作用尚不清楚.我们调查了睡眠质量是否是SES和高血压之间关联的部分中介。
方法:我们使用了美国中年II研究的数据,2004-2009年(n=426)。2023年进行了分析。参与者进行了7天的活动记录和临床评估。睡眠质量测量包括睡眠开始后的活动描记术定义的觉醒(WASO)和睡眠效率。通过三个连续的血压读数来测量高血压,SES是通过教育程度来衡量的。模型适合根据年龄进行调整,性别,种族,身体质量指数,和感知的压力。
结果:参与者的平均年龄为53.5岁(SD=12.4),其中41.0%是非裔美国人。可怜的WASO(>30分钟)的流行,睡眠效率低(<85%),高血压占77.7%,67.1%,和61.0%,分别。教育程度与高血压无关。然而,个人与低高睡眠效率的高血压患病率高24%(APR=1.24,95%CI:1.02-1.51),收缩压较高(aβ=4.61,95%CI:0.69-8.53),和较高的舒张压(aβ=2.50,95%CI:0.10-4.89)。教育与调整后的睡眠没有显着相关。没有证据表明睡眠介导SES与高血压的关系。
结论:降低高血压患病率的有效干预措施应考虑以睡眠质量为目标。未来的研究应该探索SES和种族对高血压的交叉性。
OBJECTIVE: Hypertension is highly prevalent and is a major risk factor for cardiovascular disease. There is a higher burden of hypertension among individuals of lower socioeconomic status (SES), yet the role of sleep in understanding socioeconomic disparities in hypertension is unclear. We investigated whether sleep quality is a partial mediator of the association between SES and hypertension.
METHODS: We used data from the Midlife in the United States II Study, 2004-2009 (n=426). Analyses were conducted in 2023. Participants underwent 7-day actigraphy and clinical assessments. Sleep quality measures included actigraphy-defined wakefulness after sleep onset (WASO) and sleep efficiency. Hypertension was measured via three consecutive blood pressure readings, and SES was measured via educational attainment. Models were fit adjusting for age, gender, race, body mass index, and perceived stress.
RESULTS: Participants had a mean age of 53.5 years (SD=12.4) and 41.0% were African American. The prevalences of poor WASO (>30 minutes), low sleep efficiency (<85%), and hypertension were 77.7%, 67.1%, and 61.0%, respectively.
Education was not associated with hypertension. However, individuals with low vs. high sleep efficiency had 24% higher prevalence of hypertension (aPR=1.24, 95% CI: 1.02-1.51), higher systolic blood pressure (aβ=4.61, 95% CI: 0.69-8.53), and higher diastolic blood pressure (aβ= 2.50, 95% CI: 0.10-4.89).
Education was not significantly associated with sleep after adjustment. There was no evidence of sleep mediating the SES-hypertension relation.
CONCLUSIONS: Effective interventions to lower hypertension prevalence should consider targeting sleep quality. Future research should explore the intersectionality of SES and race on hypertension.