PDF(Pubmed)
Abstract：
BACKGROUND: Mycoplasma pneumoniae pneumonia (MPP) is prevalent in paediatric patients and can progress to refractory mycoplasma pneumoniae pneumonia (RMPP).
OBJECTIVE: To assess the predictive value of bronchoscopy combined with computed tomography (CT) score in identifying RMPP in children.
METHODS: A retrospective analysis was conducted on 244 paediatric patients with MP, categorising them into RMPP and general mycoplasma pneumoniae pneumonia (GMPP) groups. A paired t-test compared the bronchitis score (BS) and CT score before and after treatment, supplemented by receiver operating characteristic (ROC) analysis.
RESULTS: The RMPP group showed higher incidences of extrapulmonary complications and pleural effusion (58.10% and 40%, respectively) compared with the GMPP group (44.60%, p = 0.037 and 18.71%, p < 0.001, respectively). The CT scores for each lung lobe were statistically significant between the groups, except for the right upper lobe (p < 0.05). Correlation analysis between the total CT score and total BS yielded r = 0.346 and p < 0.001. The ROC for BS combined with CT score, including area under the curve, sensitivity, specificity, and cut-off values, were 0.82, 0.89, 0.64, and 0.53, respectively.
CONCLUSIONS: The combined BS and CT score method is highly valuable in identifying RMPP in children.
OBJECTIVE: To assess the predictive value of bronchoscopy combined with computed tomography (CT) score in identifying RMPP in children.
METHODS: A retrospective analysis was conducted on 244 paediatric patients with MP, categorising them into RMPP and general mycoplasma pneumoniae pneumonia (GMPP) groups. A paired t-test compared the bronchitis score (BS) and CT score before and after treatment, supplemented by receiver operating characteristic (ROC) analysis.
RESULTS: The RMPP group showed higher incidences of extrapulmonary complications and pleural effusion (58.10% and 40%, respectively) compared with the GMPP group (44.60%, p = 0.037 and 18.71%, p < 0.001, respectively). The CT scores for each lung lobe were statistically significant between the groups, except for the right upper lobe (p < 0.05). Correlation analysis between the total CT score and total BS yielded r = 0.346 and p < 0.001. The ROC for BS combined with CT score, including area under the curve, sensitivity, specificity, and cut-off values, were 0.82, 0.89, 0.64, and 0.53, respectively.
CONCLUSIONS: The combined BS and CT score method is highly valuable in identifying RMPP in children.
摘要：
背景：肺炎支原体肺炎（MPP）在儿科患者中普遍存在，并可发展为难治性肺炎支原体肺炎（RMPP）。
目的：评估支气管镜结合计算机断层扫描（CT）评分对儿童RMPP的预测价值。
方法：对244例小儿MP患者进行回顾性分析，将其分为RMPP和普通肺炎支原体肺炎（GMPP）组。用配对t检验比较治疗前后的支气管炎评分(BS)和CT评分,辅以接收器工作特性(ROC)分析。
结果：RMPP组肺外并发症和胸腔积液的发生率较高（58.10%和40%，分别）与GMPP组（44.60%，p=0.037和18.71%，p分别<0.001)。各组间各肺叶的CT评分均有统计学意义,除了右上叶（p<0.05）。CT总评分与总BS之间的相关性分析得出r=0.346，p<0.001。BS结合CT评分的ROC,包括曲线下的面积，灵敏度,特异性，和截止值，分别为0.82、0.89、0.64和0.53。
结论：BS和CT评分相结合的方法在确定儿童RMPP方面具有很高的价值。
目的：评估支气管镜结合计算机断层扫描（CT）评分对儿童RMPP的预测价值。
方法：对244例小儿MP患者进行回顾性分析，将其分为RMPP和普通肺炎支原体肺炎（GMPP）组。用配对t检验比较治疗前后的支气管炎评分(BS)和CT评分,辅以接收器工作特性(ROC)分析。
结果：RMPP组肺外并发症和胸腔积液的发生率较高（58.10%和40%，分别）与GMPP组（44.60%，p=0.037和18.71%，p分别<0.001)。各组间各肺叶的CT评分均有统计学意义,除了右上叶（p<0.05）。CT总评分与总BS之间的相关性分析得出r=0.346，p<0.001。BS结合CT评分的ROC,包括曲线下的面积，灵敏度,特异性，和截止值，分别为0.82、0.89、0.64和0.53。
结论：BS和CT评分相结合的方法在确定儿童RMPP方面具有很高的价值。
