{Reference Type}: Journal Article
{Title}: Predictive value of bronchoscopy combined with CT score for refractory mycoplasma pneumoniae pneumonia in children.
{Author}: Lu W;Wu X;Xu Y;Wang T;Xiao A;Guo X;Xu Y;Li D;Li S;
{Journal}: BMC Pulm Med
{Volume}: 24
{Issue}: 1
{Year}: 2024 May 22
{Factor}: 3.32
{DOI}: 10.1186/s12890-024-02996-w
{Abstract}: <B>BACKGROUND: </B>Mycoplasma pneumoniae pneumonia (MPP) is prevalent in paediatric patients and can progress to refractory mycoplasma pneumoniae pneumonia (RMPP).<BR><B>OBJECTIVE: </B>To assess the predictive value of bronchoscopy combined with computed tomography (CT) score in identifying RMPP in children.<BR><B>METHODS: </B>A retrospective analysis was conducted on 244 paediatric patients with MP, categorising them into RMPP and general mycoplasma pneumoniae pneumonia (GMPP) groups. A paired t-test compared the bronchitis score (BS) and CT score before and after treatment, supplemented by receiver operating characteristic (ROC) analysis.<BR><B>RESULTS: </B>The RMPP group showed higher incidences of extrapulmonary complications and pleural effusion (58.10% and 40%, respectively) compared with the GMPP group (44.60%, p = 0.037 and 18.71%, p < 0.001, respectively). The CT scores for each lung lobe were statistically significant between the groups, except for the right upper lobe (p < 0.05). Correlation analysis between the total CT score and total BS yielded r = 0.346 and p < 0.001. The ROC for BS combined with CT score, including area under the curve, sensitivity, specificity, and cut-off values, were 0.82, 0.89, 0.64, and 0.53, respectively.<BR><B>CONCLUSIONS: </B>The combined BS and CT score method is highly valuable in identifying RMPP in children.