Abstract：
OBJECTIVE: To compare the analgesic effect of a bilateral ultrasound-guided erector spinae plane block (ESPB) in dogs undergoing hemilaminectomy using either a low-volume high-concentration (LV-HC) or a high-volume low-concentration (HV-LC) local anaesthetic solution.
METHODS: Retrospective observational equivalence trial.
METHODS: A total of 391 client-owned dogs undergoing hemilaminectomy.
METHODS: Dogs were assigned to group LV-HC or HV-LC depending on whether 0.2-0.25% levobupivacaine (0.4-0.5 mL kg-1) or 0.125-0.15% levobupivacaine (0.8-1 mL kg-1) was used to perform the ESPB, respectively. The number of dogs in which intraoperative rescue fentanyl boluses were administered, the total dose of fentanyl administered, the overall methadone consumption during the first 24 hours postoperatively and anaesthetic complications were recorded. Univariate and multivariate statistical analyses were performed considering p < 0.05 significant.
RESULTS: A total of 248 and 143 dogs were assigned to groups LV-HC and HV-LC, respectively. In group HV-LC, the number of dogs requiring fentanyl intraoperatively (64.3%) was higher (p = 0.0001) than that in group LV-HC (43.5%). The overall intraoperative fentanyl consumption was higher in group HV-LC between the first skin incision and the end of the lamina drilling (p = 0.028). According to the regression analysis, the group allocation was the best variable to predict the intraoperative fentanyl consumption (p < 0.001). Antimuscarinic drugs were administered more frequently in group LV-HC (p < 0.02). However, the prevalence of hypotension and other pharmacological cardiovascular interventions did not differ between groups. No differences in methadone consumption during the first 24 hours postoperatively were found between the groups.
UNASSIGNED: When performing a bilateral ESPB in dogs undergoing hemilaminectomy, compared with HV-LC, the use of LV-HC local anaesthetic solution reduces the intraoperative fentanyl consumption without affecting the postoperative methadone requirement.
METHODS: Retrospective observational equivalence trial.
METHODS: A total of 391 client-owned dogs undergoing hemilaminectomy.
METHODS: Dogs were assigned to group LV-HC or HV-LC depending on whether 0.2-0.25% levobupivacaine (0.4-0.5 mL kg-1) or 0.125-0.15% levobupivacaine (0.8-1 mL kg-1) was used to perform the ESPB, respectively. The number of dogs in which intraoperative rescue fentanyl boluses were administered, the total dose of fentanyl administered, the overall methadone consumption during the first 24 hours postoperatively and anaesthetic complications were recorded. Univariate and multivariate statistical analyses were performed considering p < 0.05 significant.
RESULTS: A total of 248 and 143 dogs were assigned to groups LV-HC and HV-LC, respectively. In group HV-LC, the number of dogs requiring fentanyl intraoperatively (64.3%) was higher (p = 0.0001) than that in group LV-HC (43.5%). The overall intraoperative fentanyl consumption was higher in group HV-LC between the first skin incision and the end of the lamina drilling (p = 0.028). According to the regression analysis, the group allocation was the best variable to predict the intraoperative fentanyl consumption (p < 0.001). Antimuscarinic drugs were administered more frequently in group LV-HC (p < 0.02). However, the prevalence of hypotension and other pharmacological cardiovascular interventions did not differ between groups. No differences in methadone consumption during the first 24 hours postoperatively were found between the groups.
UNASSIGNED: When performing a bilateral ESPB in dogs undergoing hemilaminectomy, compared with HV-LC, the use of LV-HC local anaesthetic solution reduces the intraoperative fentanyl consumption without affecting the postoperative methadone requirement.
摘要：
目的：比较双侧超声引导下的竖脊肌平面阻滞（ESPB）在使用低容量高浓度（LV-HC）或高容量低浓度（HV-LC）局部麻醉溶液进行半椎板切除术的犬中的镇痛效果。
方法：回顾性观察性等效试验。
方法：共有391只受助犬接受半椎板切除术。
方法：根据是否使用0.2-0.25％左旋布比卡因（0.4-0.5mLkg-1）或0.125-0.15％左旋布比卡因（0.8-1mLkg-1）进行ESPB，将狗分为LV-HC组或HV-LC组。分别。术中给予芬太尼大丸剂的狗的数量，芬太尼的总剂量，记录术后前24小时美沙酮的总体消耗量和麻醉并发症.进行单变量和多变量统计分析,认为p<0.05显著。
结果：总共248只和143只狗被分配到LV-HC和HV-LC组，分别。HV-LC组中,术中需要芬太尼的犬只(64.3%)高于LV-HC组(43.5%)(p=0.0001).在第一次皮肤切口和椎板钻孔结束之间，HV-LC组的术中芬太尼总消耗量较高（p=0.028）。根据回归分析，组分配是预测术中芬太尼消耗量的最佳变量(p<0.001).抗毒蕈碱药物在LV-HC组中施用更频繁(p<0.02)。然而,低血压和其他心血管药物干预的患病率在组间没有差异.两组在术后前24小时内美沙酮的消耗量没有差异。
■在接受半椎板切除术的狗中进行双侧ESPB时，与HV-LC相比，LV-HC局部麻醉溶液的使用减少了术中芬太尼的消耗量,而不影响术后美沙酮的需求.
方法：回顾性观察性等效试验。
方法：共有391只受助犬接受半椎板切除术。
方法：根据是否使用0.2-0.25％左旋布比卡因（0.4-0.5mLkg-1）或0.125-0.15％左旋布比卡因（0.8-1mLkg-1）进行ESPB，将狗分为LV-HC组或HV-LC组。分别。术中给予芬太尼大丸剂的狗的数量，芬太尼的总剂量，记录术后前24小时美沙酮的总体消耗量和麻醉并发症.进行单变量和多变量统计分析,认为p<0.05显著。
结果：总共248只和143只狗被分配到LV-HC和HV-LC组，分别。HV-LC组中,术中需要芬太尼的犬只(64.3%)高于LV-HC组(43.5%)(p=0.0001).在第一次皮肤切口和椎板钻孔结束之间，HV-LC组的术中芬太尼总消耗量较高（p=0.028）。根据回归分析，组分配是预测术中芬太尼消耗量的最佳变量(p<0.001).抗毒蕈碱药物在LV-HC组中施用更频繁(p<0.02)。然而,低血压和其他心血管药物干预的患病率在组间没有差异.两组在术后前24小时内美沙酮的消耗量没有差异。
■在接受半椎板切除术的狗中进行双侧ESPB时，与HV-LC相比，LV-HC局部麻醉溶液的使用减少了术中芬太尼的消耗量,而不影响术后美沙酮的需求.
