Abstract：
Members of both the Piezo and transmembrane channel-like (TMC) families are bona fide mammalian mechanotransducers. In a recent study, Zhang, Shao et al. discovered that TMC7, a non-mechanosensitive TMC, inhibits Piezo2-dependent mechanosensation, with implications for the importance of cellular context for Piezo2 channels in normal and pathological responses to mechanical pain.
摘要：
压电和跨膜通道样（TMC）家族的成员都是真正的哺乳动物机械转导者。在最近的一项研究中,张，Shaoetal.发现TMC7，一种非机械敏感性TMC，抑制Piezo2依赖的机械感觉，在机械性疼痛的正常和病理反应中，Piezo2通道的细胞环境的重要性。
