{Reference Type}: Journal Article
{Title}: A novel suppressor of Piezo2 in rodent nociceptors.
{Author}: West AK;Schneider ER;
{Journal}: Trends Neurosci
{Volume}: 47
{Issue}: 7
{Year}: 2024 Jul 17
{Factor}: 16.978
{DOI}: 10.1016/j.tins.2024.05.003
{Abstract}: Members of both the Piezo and transmembrane channel-like (TMC) families are bona fide mammalian mechanotransducers. In a recent study, Zhang, Shao et al. discovered that TMC7, a non-mechanosensitive TMC, inhibits Piezo2-dependent mechanosensation, with implications for the importance of cellular context for Piezo2 channels in normal and pathological responses to mechanical pain.