%0 Journal Article
%T A novel suppressor of Piezo2 in rodent nociceptors.
%A West AK
%A Schneider ER
%J Trends Neurosci
%V 47
%N 7
%D 2024 Jul 17
%M 38762363
%F 16.978
%R 10.1016/j.tins.2024.05.003
%X Members of both the Piezo and transmembrane channel-like (TMC) families are bona fide mammalian mechanotransducers. In a recent study, Zhang, Shao et al. discovered that TMC7, a non-mechanosensitive TMC, inhibits Piezo2-dependent mechanosensation, with implications for the importance of cellular context for Piezo2 channels in normal and pathological responses to mechanical pain.