PDF(Pubmed)
Abstract：
Heterosis boosts crop yield; however, harnessing additional progressive heterosis in polyploids is challenging for breeders. We bioengineered a \'mitosis instead of meiosis\' (MiMe) system that generates unreduced, clonal gametes in three hybrid tomato genotypes and used it to establish polyploid genome design. Through the hybridization of MiMe hybrids, we generated \'4-haplotype\' plants that encompassed the complete genetics of their four inbred grandparents, providing a blueprint for exploiting polyploidy in crops.
摘要：
杂种优势提高了作物产量；然而，利用多倍体中额外的进行性杂种优势对育种者来说是一个挑战。我们生物工程\'有丝分裂而不是减数分裂\'（MiMe）系统，产生未还原，3种杂交番茄基因型的克隆配子，并用于建立多倍体基因组设计。通过MiMe杂种的杂交，我们产生了“4-单倍型”植物，涵盖了他们四个近交祖父母的完整遗传学，提供了利用作物多倍体的蓝图。
