PDF(Pubmed)
Abstract：
OBJECTIVE: There was no evidence regarding the relationship between septic shock and tracheal injury scores. Investigate whether septic shock was independently associated with tracheal injury scores in intensive care unit (ICU) patients with invasive ventilation.
METHODS: Prospective observational cohort study.
METHODS: Our study was conducted in a Class III hospital in Hebei province, China.
METHODS: Patients over 18 years of age admitted to the ICU between 31 May 2020 and 3 May 2022 with a tracheal tube and expected to be on the tube for more than 24 hours.
METHODS: Tracheal injuries were evaluated by examining hyperaemia, ischaemia, ulcers and tracheal perforation by fiberoptic bronchoscope. Depending on the number of lesions, the lesions were further classified as moderate, severe or confluent.
RESULTS: Among the 97 selected participants, the average age was 56.6±16.5 years, with approximately 64.9% being men. The results of adjusted linear regression showed that septic shock was associated with tracheal injury scores (β: 2.99; 95% CI 0.70 to 5.29). Subgroup analysis revealed a stronger association with a duration of intubation ≥8 days (p=0.013).
CONCLUSIONS: Patients with septic shock exhibit significantly higher tracheal injury scores compared with those without septic shock, suggesting that septic shock may serve as an independent risk factor for tracheal injury.
BACKGROUND: ChiCTR2000037842, registered 03 September 2020. Retrospectively registered, https://www.chictr.org.cn/edit.aspx?pid=57011&htm=4.
METHODS: Prospective observational cohort study.
METHODS: Our study was conducted in a Class III hospital in Hebei province, China.
METHODS: Patients over 18 years of age admitted to the ICU between 31 May 2020 and 3 May 2022 with a tracheal tube and expected to be on the tube for more than 24 hours.
METHODS: Tracheal injuries were evaluated by examining hyperaemia, ischaemia, ulcers and tracheal perforation by fiberoptic bronchoscope. Depending on the number of lesions, the lesions were further classified as moderate, severe or confluent.
RESULTS: Among the 97 selected participants, the average age was 56.6±16.5 years, with approximately 64.9% being men. The results of adjusted linear regression showed that septic shock was associated with tracheal injury scores (β: 2.99; 95% CI 0.70 to 5.29). Subgroup analysis revealed a stronger association with a duration of intubation ≥8 days (p=0.013).
CONCLUSIONS: Patients with septic shock exhibit significantly higher tracheal injury scores compared with those without septic shock, suggesting that septic shock may serve as an independent risk factor for tracheal injury.
BACKGROUND: ChiCTR2000037842, registered 03 September 2020. Retrospectively registered, https://www.chictr.org.cn/edit.aspx?pid=57011&htm=4.
摘要：
目的：没有关于脓毒性休克与气管损伤评分之间关系的证据。在有创通气的重症监护病房（ICU）患者中，调查感染性休克是否与气管损伤评分独立相关。
方法：前瞻性观察性队列研究。
方法：我们的研究是在河北省某三级医院进行的，中国。
方法：在2020年5月31日至2022年5月3日期间，18岁以上的患者使用气管导管进入ICU，预计将在导管上放置24小时以上。
方法：通过检查充血来评估气管损伤，缺血,纤维支气管镜溃疡和气管穿孔。根据病变的数量,病变进一步分类为中度，严重的或汇合的。
结果：在选定的97名参与者中，平均年龄为56.6±16.5岁，大约64.9%是男性。校正线性回归结果显示感染性休克与气管损伤评分相关(β:2.99;95%CI0.70~5.29)。亚组分析显示与插管时间≥8天的相关性更强（p=0.013）。
结论：与没有感染性休克的患者相比，感染性休克患者的气管损伤评分明显更高，提示感染性休克可能是气管损伤的独立危险因素。
背景：ChiCTR2000037842，注册于2020年9月3日。追溯登记,https://www.chictr.org.cn/edit。aspx?pid=57011&htm=4。
方法：前瞻性观察性队列研究。
方法：我们的研究是在河北省某三级医院进行的，中国。
方法：在2020年5月31日至2022年5月3日期间，18岁以上的患者使用气管导管进入ICU，预计将在导管上放置24小时以上。
方法：通过检查充血来评估气管损伤，缺血,纤维支气管镜溃疡和气管穿孔。根据病变的数量,病变进一步分类为中度，严重的或汇合的。
结果：在选定的97名参与者中，平均年龄为56.6±16.5岁，大约64.9%是男性。校正线性回归结果显示感染性休克与气管损伤评分相关(β:2.99;95%CI0.70~5.29)。亚组分析显示与插管时间≥8天的相关性更强（p=0.013）。
结论：与没有感染性休克的患者相比，感染性休克患者的气管损伤评分明显更高，提示感染性休克可能是气管损伤的独立危险因素。
背景：ChiCTR2000037842，注册于2020年9月3日。追溯登记,https://www.chictr.org.cn/edit。aspx?pid=57011&htm=4。
