UNASSIGNED: We sought to synthesize the existing literature on severe pertussis in infants and inform further study.
UNASSIGNED: A scoping review was performed based on the methodological framework developed by Arksey & O\'Malley. Search in Pubmed and Embase databases, with no restrictions on the language and date of publication.
UNASSIGNED: Of the 1299 articles retrieved, 64 were finally included. The selected articles were published between 1979 and 2022, with 90.6% (58/64) of the studies in the last two decades. The studies covered epidemiology, pathology, clinical characteristics, risk factors, treatments, and burden of disease.
UNASSIGNED: The literature reviewed suggests that studies on severe pertussis in infants covered a variety of clinical concerns. However, these studies were observational, and experimental studies are needed to provide high-quality evidence.
■我们试图综合有关婴儿重度百日咳的现有文献,并为进一步的研究提供参考。
■根据Arksey&O\'Malley开发的方法框架进行了范围审查。在Pubmed和Embase数据库中搜索,对语言和发布日期没有限制。
■在检索到的1299篇文章中,最终有64人加入。选定的文章发表于1979年至2022年之间,在过去的二十年中,有90.6%(58/64)的研究。这些研究涵盖了流行病学,病理学,临床特征,危险因素,治疗,和疾病负担。
■文献综述表明,对婴儿重度百日咳的研究涵盖了各种临床问题。然而,这些研究是观察性的,需要实验研究来提供高质量的证据。